ArticleEuropean journal of epidemiology2023
The association between night shift work and breast cancer risk in the Finnish twins cohort.
Article in European journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Chronotype differences in the risk of cancers, diabetes mellitus, and poor mental health among shift workers: a meta-analysis.Scandinavian journal of work, environment & health · 2026Pooled it
- Night shift work and breast cancer risk: A cohort study based on payroll and survey data from Finland.Scandinavian journal of work, environment & health · 2026Article
- Identifying druggable proteins of the association of chronotype on breast cancer using Mendelian randomization.Communications medicine · 2026Article
- Association between nocturnal ozone enhancement and daily cardiovascular mortality: A multi-city study in China.Eco-Environment & Health · 2026Article
- Modifiable and Nonmodifiable Risk Factors for Breast Cancer: A Comprehensive Scoping Review.International journal of breast cancer · 2026Review
- Night shift work and breast cancer: from etiopathology to precision risk analysis.NPJ breast cancer · 2025Review
- The multifaceted impact of circadian disruption on cancer risk: a systematic review of insights and economic implications.Journal of the National Cancer Center · 2025Review
- Night Shift Work Associates with All-Cause and Cause-Specific Mortality: A Large Prospective Cohort Study.Journal of general internal medicine · 2025Article
- A narrative review of sleep and breast cancer: from epidemiology to mechanisms.Cancer causes & control : CCC · 2025Review
- Sleep factors and risk of thyroid cancer, nodules and dysfunction: Mendelian randomization study.Gland surgery · 2025Article
- Night shift work and breast cancer risk - 2023 update of epidemiologic evidence.Journal of the National Cancer Center · 2025Review
- Small-area spatio-temporal analysis of cancer risk to support effective and equitable cancer prevention.PloS one · 2025Article
- Current trends in breast cancer genetics, risk factors, and screening strategies.Journal of biological methods · 2025Review
- Emergency Departments in Contemporary Healthcare: Are They Still for Emergencies? An Analysis of over 1 Million Attendances.Healthcare (Basel, Switzerland) · 2024Article
- Pre-diagnosis blood DNA methylation profiling of twin pairs discordant for breast cancer points to the importance of environmental risk factors.Clinical epigenetics · 2024Article
- Impact of Modern Lifestyle on Circadian Health and Its Contribution to Adipogenesis and Cancer Risk.Cancers · 2024Review
- Circadian period is compensated for repressor protein turnover rates in single cells.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Biological clock regulation by theFrontiers in cell and developmental biology · 2024Review
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
Abstract
Breast cancer is highly prevalent yet a more complete understanding of the interplay between genes and probable environmental risk factors, such as night work, remains lagging. Using a discordant twin pair design, we examined the association between night shift work and breast cancer risk, controlling for familial confounding. Shift work pattern was prospectively assessed by mailed questionnaires among 5,781 female twins from the Older Finnish Twin Cohort. Over the study period (1990-2018), 407 incident breast cancer cases were recorded using the Finnish Cancer Registry. Cox proportional hazards models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) adjusting for potential confounders. Within-pair co-twin analyses were employed in 57 pairs to account for potential familial confounding. Compared to women who worked days only, women with shift work that included night shifts had a 1.58-fold higher risk of breast cancer (HR = 1.58; 95%CI, 1.16-2.15, highest among the youngest women i.e. born 1950-1957, HR = 2.08; 95%CI, 1.32-3.28), whereas 2-shift workers not including night shifts, did not (HR = 0.84; 95%CI, 0.59-1.21). Women with longer sleep (average sleep duration > 8 h/night) appeared at greatest risk of breast cancer if they worked night shifts (HR = 2.91; 95%CI, 1.55-5.46; P
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Registered trials
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