Evidence map›Paper›PMID 36964747›Full record

SynthesisInquiry : a journal of medical care organization, provision and financing

Global Incidence of Surgical Site Infection Among Patients: Systematic Review and Meta-Analysis.

Dechasa Adare Mengistu, Addisu Alemu, Abdi Amin Abdukadir, Ahmed Mohammed Husen, Fila Ahmed, Baredin Mohammed, Ibsa Musa

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Inquiry : a journal of medical care organization, provision and financing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07325786 (A Novel Method for the Examination of Infected Wound Specimens), which is not on this map. Cited by 64 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 10 pooled it
32.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07325786 naactive not recruitingnot on this map

A Novel Method for the Examination of Infected Wound Specimens: Percutaneous Wound Sampling With Analysis in Blood Culture (PERKA-B) Method

TypeinterventionalSponsorProf. Dr. Bülent M. ErtuğrulRan2025 to 2026Enrolled300ConditionsWound Infection Bacterial, IdentificationArmsTissue culture collection
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 10 syntheses or guidelines pooled it, 102 citations in OpenAlex.

  1. Pooled it
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  5. Negative pressure wound therapy for the prevention of surgical site infections in orthopedic and trauma surgery: a systematic review and meta-analysis of RCTs.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
    Pooled it
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  7. A network meta-analysis of the timing of wound dressing removal.Annals of the Royal College of Surgeons of England · 2025
    Pooled it
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dechasa Adare MengistuHaramaya University, Harar, Ethiopia.ORCID 0000-0002-0076-5586
Addisu AlemuHaramaya University, Harar, Ethiopia.
Abdi Amin AbdukadirHaramaya University, Harar, Ethiopia.ORCID 0000-0002-0539-4059
Ahmed Mohammed HusenHaramaya University, Harar, Ethiopia.
Fila AhmedHaramaya University, Harar, Ethiopia.
Baredin MohammedHaramaya University, Harar, Ethiopia.
Ibsa MusaHaramaya University, Harar, Ethiopia.
Haramaya University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare-associated infections pose one of the most severe threats to patients' health and remain a major challenge for healthcare providers globally. Among healthcare-associated infections, surgical site infection is one of the most commonly reported infections. It remains a major cause of morbidity and mortality across the world. The aim of this study was to provide a pooled incidence of surgical site infection among patients on a regional and global scale. This study was conducted under the PRISMA guidelines developed for systematic review and meta-analysis. The studies were searched using electronic databases (SCOPUS, PubMed/MEDLINE, Web of Science, Google Scholar, DOAJ, and MedNar) from June 1st, 2022 to August 4th, 2022, using Boolean logic operators (AND, OR, and NOT), Medical Subject Headings (MeSH), and keywords. The quality of the study was assessed using the Joanna Briggs Institute Critical Assessment tool to determine the relevance of each included article to the study. A comprehensive meta-analysis version 3 was used to estimate the pooled prevalence of surgical site infections among the patients. A total of 2124 articles were retrieved from the included electronic databases. Finally, after applying inclusion criteria, 43 articles conducted in 39 countries were included in the current study. The global pooled incidence of SSI was found to be 2.5% (95% CI: 1.6, 3.7). Based on the subgroup analysis by WHO region and survey period, the incidence of SSI was 2.7% (95% CI: 2.2, 3.3%) and 2.5% (95% CI: 1.8, 3.5%), respectively. The highest incidence was reported in the African Region (7.2% [95% CI: 4.3, 11.8%]) and among studies conducted between 1996 and 2001 (2.9% [95% CI: 0.9%, 8.8%]). This study revealed that the overall pooled incidence of SSI was 2.5%. SSI estimates varied among the WHO regions of the world. However, the highest incidence (2.7%) was observed in the African region. This indicates that there is a need to implement safety measures, including interventions for SSI prevention to reduce SSI and improve patient safety.

Indexed as

Cross InfectionSurgical Wound InfectionHumansIncidencePrevalenceglobalhospital acquired infectionnosocomial infectionpatientpatient safetysurgical site infection

Identifiers

PMID36964747
PMCPMC10041599
OpenAlexW4360941921

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.