ArticleBMC nephrology2023
Systemic immune-inflammation index may predict the acute kidney injury and prognosis in patients with spontaneous cerebral hemorrhage undergoing craniotomy: a single-center retrospective study.
Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 18 citations in OpenAlex.
- Construction and Validation of a Nomogram Based on Preoperative Inflammatory Indicators for Predicting Acute Kidney Injury After Pancreaticoduodenectomy.Journal of inflammation research · 2026Article
- Association Between Systemic Immune-Inflammation Index and in-Hospital and Long-Term All-Cause Mortality in Patients with Type 2 Diabetes Mellitus Complicated by Spontaneous Intracerebral Hemorrhage.Journal of inflammation research · 2026Article
- A Risk Prediction Model for MDRJournal of multidisciplinary healthcare · 2026Article
- Machine learning-based prediction of acute kidney injury after intracerebral hemorrhage: Comparison of multiple model approaches.Medicine · 2025Article
- Review
- A low preoperative platelet-to-white blood cell ratio is associated with acute kidney injury following cerebral aneurysm treatment in South Korea.Acute and critical care · 2025Article
- Correlation of Novel Inflammation Index with Postoperative Acute Kidney Injury in Patients with Joint Arthroplasty: A Retrospective Cohort Study.Journal of inflammation research · 2025Article
- Hospitalized acute exacerbation in chronic obstructive pulmonary disease - impact on long-term renal outcomes.Respiratory research · 2024Article
- Predictive Value of the Systemic Immune-Inflammation Index in the 28-Day Mortality for Patients with Sepsis-Associated Acute Kidney Injury and Construction of a Prediction Model.Journal of inflammation research · 2024Article
- Acute kidney injury after intracerebral hemorrhage: a mini review.Frontiers in medicine · 2024Review
- Association between systemic immune-inflammation index and chronic kidney disease: A population-based study.PloS one · 2024Article
- Predictive value of the dynamic systemic immune-inflammation index in the prognosis of patients with intracerebral hemorrhage: a 10-year retrospective analysis.Frontiers in neurology · 2024Article
- Prediction of Acute Kidney Injury in Intracerebral Hemorrhage Patients Using Machine Learning.Neuropsychiatric disease and treatment · 2023Article
- Risk factors, complications and biomarkers associated with acute kidney injury after craniotomy: a comprehensive mini-review.Acute medicine & surgeryReview
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Authors and funding
6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe systemic immune-inflammation index (SII) is an emerging prognostic marker of cancer. We aimed to explore the predictive ability of the SII on acute kidney injury (AKI) and prognosis in patients with spontaneous cerebral hemorrhage (SCH) who underwent craniotomy.
methodsPatients with SCH who underwent craniotomy between 2014 and 2021 were enrolled in this study. The epidemiology and predictive factors for AKI after SCH were analyzed. The prognostic factors for clinical outcomes in patients with SCH and AKI were further investigated. The prognostic factors were then analyzed using a logistic regression model and a receiver operating characteristic curve.
resultsIn total, 305 patients were enrolled in this study. Of these, 129 (42.3%) patients presented with AKI, and 176 (57.7%) patients were unremarkable. The SII (odds ratio [OR], 1.261; 95% confidence interval [CI], 1.036-1.553; P = 0.020) values and serum uric acid levels (OR, 1.004; 95% CI, 1.001-1.007; P = 0.005) were significant predictors of AKI after SCH craniotomy. The SII cutoff value was 1794.43 (area under the curve [AUC], 0.669; 95% CI, 0.608-0.730; P < 0.001; sensitivity, 65.9%; specificity, 65.1%). Of the patients with AKI, 95 and 34 achieved poor and good outcomes, respectively. SII values (OR, 2.667; 95% CI, 1.167-6.095; P = 0.020), systemic inflammation response index values (OR, 1.529; 95% CI, 1.064-2.198; P = 0.022), and Glasgow Coma Scale (GCS) scores on admission (OR, 0.593; 95% CI, 0.437-0.805; P = 0.001) were significant in the multivariate logistic regression analysis. The cutoff SII value was 2053.51 (AUC, 0.886; 95% CI, 0.827-0.946; P < 0.001; sensitivity, 78.9%; specificity, 88.2%).
conclusionsThe SII may predict AKI in patients with SCH who underwent craniotomy and may also predict the short-term prognosis of these patients.
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