ArticleJournal of materials science. Materials in medicine2023
Novel adhesive mineral-organic bone cements based on phosphoserine and magnesium phosphates or oxides.
Article in Journal of materials science. Materials in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- An osteogenesis mimicking biomineralized bone adhesive for rapid skeletal regeneration.Bioengineering & translational medicine · 2026Article
- Development and Characterization of Water-Based Porous Calcium Phosphate Bone Cements for Peri-Implant Regeneration: An In Situ Study.Biomimetics (Basel, Switzerland) · 2026Article
- Magnesium-organophosphate bone adhesives repurposed as endodontic cements for dental applications.Clinical oral investigations · 2026Article
- Hydrostable hard tissue adhesives based on organophosphates and magnesium phosphates with strong bonding and cellular compatibility.Scientific reports · 2025Article
- Bone filler and adhesive at the same time: in-vitro analysis in a porcine fracture model.BMC musculoskeletal disorders · 2025Article
- Biomechanical Performance and Handling of Mineral-Organic Adhesive Bone Cements Based on Magnesium Under Clinical Test Conditions.Journal of clinical medicine · 2025Article
- A magnesium calcium phosphate-based cement as a bone adhesive: characterization and biomechanical evaluation.BMC musculoskeletal disorders · 2025Article
- Biomimetic synthetic test system based on hydroxyapatite cement for adhesive strength evaluation of experimental mineral-organic bone adhesive materials.Journal of biomaterials applications · 2025Article
- A particle-filled hydrogel based on alginate and calcium phosphate nanoparticles as bone adhesive.Journal of materials science. Materials in medicine · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Present surgical situations require a bone adhesive which has not yet been developed for use in clinical applications. Recently, phosphoserine modified cements (PMC) based on mixtures of o-phosphoserine (OPLS) and calcium phosphates, such as tetracalcium phosphate (TTCP) or α-tricalcium phosphate (α-TCP) as well as chelate setting magnesium phosphate cements have gained increasing popularity for their use as mineral bone adhesives. Here, we investigated new mineral-organic bone cements based on phosphoserine and magnesium phosphates or oxides, which possess excellent adhesive properties. These were analyzed by X-ray diffraction, Fourier infrared spectroscopy and electron microscopy and subjected to mechanical tests to determine the bond strength to bone after ageing at physiological conditions. The novel biomineral adhesives demonstrate excellent bond strength to bone with approximately 6.6-7.3 MPa under shear load. The adhesives are also promising due to their cohesive failure pattern and ductile character. In this context, the new adhesive cements are superior to currently prevailing bone adhesives. Future efforts on bone adhesives made from phosphoserine and Mg
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.