Evidence map›Paper›PMID 36964270›Full record

ArticleEuropean journal of clinical nutrition2023

Food hypersensitivity: an examination of factors influencing symptoms and temporal changes in the prevalence of sensitization in an adult sample.

Holly C Y Lam, Catherine Neukirch, Christer Janson, Judith Garcia-Aymerich, Michael Clausen, N Sabrina Idrose, Pascal Demoly, Randi J Bertelsen, Lidia C Ruiz, Chantal Raherison and 1 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Prevalence and Associated Factors of Oral Allergy Syndrome among Mexican Adults: A Survey-Based Study: Oral Allergy Syndrome.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 11 institutions in 9 countries.

Holly C Y LamNational Heart and Lung Institute, Imperial College London, London, UK. ching.lam@imperial.ac.uk.ORCID 0000-0002-8305-9280
Catherine NeukirchService de Pneumologie, AP-HP, Hôpital Bichat, Université de Paris, INSERM 1152, F-75018, Paris, France.
Christer JansonDepartment of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
Judith Garcia-AymerichBarcelona Institute of Global Health (ISGlobal), Doctor Aiguader, 88, 08003, Barcelona, Spain.
Michael ClausenChildren's Hospital and Department of Allergy, Landspitali University Hospital, 101, Reykjavik, Iceland.
N Sabrina IdroseAllergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia.
Pascal DemolyHôpital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France.
Randi J BertelsenDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Lidia C RuizSocial Epidemiology and Health Policy (SEHPO), Department of Family Medicine and Population Health (FAMPOP), University of Antwerp, Antwerp, Belgium.
Chantal RaherisonUniversity of Bordeaux, INSERM, BPH, U1219, F-33000, Bordeaux, France.
Deborah L JarvisNational Heart and Lung Institute, Imperial College London, London, UK.
Centre Hospitalier Universitaire de Montpellier · FRHaukeland University Hospital · NOInserm · FRLung Institute · USMRC Centre for Environment and HealthReykjavík University · ISThe University of Melbourne · AUUniversitat Pompeu Fabra · ESUniversité de Bordeaux · FRUniversity of Antwerp · BEUppsala University · SE

Funding

Medical Research Council
6 · The paper itself

Abstract

BACKGROUND/

objectivesFood hypersensitivity (FHS) is common, but little is known about the factors associated with severe reactions, age of onset and whether sensitization persists. This study examines the factors associated with self-reported severe food reactions, onset age and the changes in prevalence of sensitization to foods over time in an adult sample. SUBJECTS/

methodsWe used data from adults taking part in the European Community Respiratory Health Survey (ECRHS) III (2010-2014) who provided information on food hypersensitivity, including symptoms, suspected culprit food and onset age (n = 4865). A subsample from six countries had serum food-specific IgE tested for 25 core foods and also in 10 years earlier (ECRHS II). We applied logistic regression and McNemar's test for analyses.

resultsThe prevalence of self-reported FHS was 13.5% at ECRHS III. Of those providing information on symptoms (n = 611), 26.4% reported severe reactions. About 80% of 1033 reported food-specific reactions (reported by 596 participants) began after age 15. History of asthma (odds ratio OR 2.12 95% confidence interval CI 1.13-3.44) and a younger age of onset of FHS (OR 1.02, 95% CI 1.01-1.03, per year) were associated with higher risks of a lifetime experience of severe food reactions. In the subsample with IgE tested in both surveys (n = 1612), the overall prevalence of sensitization to foods did not change over 10 years.

conclusionOur findings support previous observations of more severe food reactions in people with asthma and that most FHS reported by this sample started after age 15. We found no evidence of changes in the prevalence of sensitization to food in adults followed for 10 years.

Indexed as

AsthmaFood HypersensitivityHypersensitivityAdolescentAdultAllergensFoodHumansImmunoglobulin EPrevalenceAllergensImmunoglobulin E

Identifiers

PMID36964270
PMCPMC10393775
OpenAlexW4360827106

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.