Evidence map›Paper›PMID 36964219›Full record

ArticleScientific reports2023

Machine learning for post-acute pancreatitis diabetes mellitus prediction and personalized treatment recommendations.

Jun Zhang, Yingqi Lv, Jiaying Hou, Chi Zhang, Xuelu Yua, Yifan Wang, Ting Yang, Xianghui Su, Zheng Ye, Ling Li

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Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jun ZhangDepartment of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Yingqi LvDepartment of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Jiaying HouDepartment of Endocrinology, Changji Branch, First Affiliated Hospital of Xinjiang Medical University, Xinjiang, 831100, China.
Chi ZhangDepartment of Endocrinology, Hunan Provincial People's Hospital, First Affiliated Hospital of Hunan Normal University, Changsha, 410005, Hunan, China.
Xuelu YuaDepartment of Endocrinology, Yixing Second People's Hospital, Wuxi, 214200, China.
Yifan WangDepartment of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Ting YangDepartment of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Xianghui SuDepartment of Endocrinology, Changji Branch, First Affiliated Hospital of Xinjiang Medical University, Xinjiang, 831100, China.
Zheng YeDepartment of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China. charles_ye@126.com.ORCID 0000-0001-5532-6428
Ling LiDepartment of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China. dr_liling@126.com.ORCID 0000-0003-0083-6978

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-acute pancreatitis diabetes mellitus (PPDM-A) is the main component of pancreatic exocrine diabetes mellitus. Timely diagnosis of PPDM-A improves patient outcomes and the mitigation of burdens and costs. We aimed to determine risk factors prospectively and predictors of PPDM-A in China, focusing on giving personalized treatment recommendations. Here, we identify and evaluate the best set of predictors of PPDM-A prospectively using retrospective data from 820 patients with acute pancreatitis at four centers by machine learning approaches. We used the L1 regularized logistic regression model to diagnose early PPDM-A via nine clinical variables identified as the best predictors. The model performed well, obtaining the best AUC = 0.819 and F1 = 0.357 in the test set. We interpreted and personalized the model through nomograms and Shapley values. Our model can accurately predict the occurrence of PPDM-A based on just nine clinical pieces of information and allows for early intervention in potential PPDM-A patients through personalized analysis. Future retrospective and prospective studies with multicentre, large sample populations are needed to assess the actual clinical value of the model.

Indexed as

Diabetes MellitusPancreatitisAcute DiseaseHumansMachine LearningPrecision MedicineProspective StudiesRetrospective Studies

Identifiers

PMID36964219
PMCPMC10038980

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.