ArticleNature communications2023
Modulation of metal species as control point for Ni-catalyzed stereodivergent semihydrogenation of alkynes with water.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Water as a Sustainable Hydrogen Donor in Transfer Hydrogenation and Reduction Reactions.Chemical record (New York, N.Y.) · 2026Review
- Reversible On/Off Switching of Ferroelectricity in a Molecular FeCo Prussian Blue Analogue with Multiple Control.Nature communications · 2026Article
- Article
- The stereo-divergent functionalization of alkynes: a comprehensive review.RSC advances · 2025Review
- Recent advances in synthetic approaches for bioactive cinnamic acid derivatives.Beilstein journal of organic chemistry · 2025Review
- Scalable deoxygenative alkynylation of alcohols via flow photochemistry.Communications chemistry · 2024Article
- Reversible C-CN Bond Cleavage by a Formal Dinickel(I) Hydride Cation.Organometallics · 2024Article
- Spin-Crossing in the (Inorganic chemistry · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
A base-assisted metal species modulation mechanism enables Ni-catalyzed stereodivergent transfer semihydrogenation of alkynes with water, delivering both olefinic isomers smoothly using cheap and nontoxic catalysts and additives. Different from most precedents, in which E-alkenes derive from the isomerization of Z-alkene products, the isomers were formed in orthogonal catalytic pathways. Mechanistic studies suggest base as a key early element in modulation of the reaction pathways: by adding different bases, nickel species with disparate valence states could be accessed to initiate two catalytic cycles toward different stereoisomers. The practicability of the method is showcased with nearly 70 examples, including internal and terminal triple bonds, enynes and diynes, affording semi-hydrogenated products in high yields and selectivity.
Identifiers
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Registered trials
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