Evidence map›Paper›PMID 36964136›Full record

ArticleScientific reports2023

Exploring alternative insecticide delivery options in a "lethal house lure" for malaria vector control.

Welbeck A Oumbouke, Antoine M G Barreaux, Innocent T Zran, Alphonsine A Koffi, Yao N'Guessan, Ludovic P Ahoua Alou, Rosine Z Wolie, Jackie Cook, Eleanore D Sternberg, Matthew B Thomas and 1 more

Open access · goldFull text read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Welbeck A OumboukeDepartment of Disease Control, London School of Hygiene and Tropical Medicine, London, UK. welbeck.oumbouke@ivcc.com.
Antoine M G BarreauxDepartment of Entomology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
Innocent T ZranInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Alphonsine A KoffiInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Yao N'GuessanInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Ludovic P Ahoua AlouInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Rosine Z WolieInstitut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.
Jackie CookMedical Research Council (MRC) International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK.
Eleanore D SternbergDepartment of Entomology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
Matthew B ThomasDepartment of Entomology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, PA, 16802, USA.
Raphael N'GuessanDepartment of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.
Institut National de Santé Publique · CILondon School of Hygiene & Tropical Medicine · GBCenter for Disease Dynamics, Economics & Policy · USCentre Occitanie-Montpellier · FRPennsylvania State University · USUniversité Félix Houphouët-Boigny · CI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The In2Care EaveTube is a house modification designed to block and kill malaria mosquitoes using an electrostatic netting treated with insecticide powder. A previous study demonstrated prolonged duration of effective action of insecticide-treated electrostatic netting in a semi-field setting. As part of a cluster randomized controlled trial (CRT) of the EaveTube intervention in Côte d'Ivoire, we investigated the residual efficacy of a pyrethroid insecticide deployed in EaveTubes under village conditions of use. We also explored the scope of using existing malaria control technologies including LLINs and IRS as alternative methods to deliver insecticides in the lethal house lure. The efficacy of beta-cyfluthrin was monitored over time using the "eave tube bioassay" method. Mortality of beta-cyfluthrin exposed pyrethroid resistant Anopheles gambiae mosquitoes was > 80% after 4 months. The impact (mosquito mortality) of PVC tubes coated with pirimiphos methyl was similar to that of beta-cyfluthrin treated insert (66.8 vs. 62.8%) in release-recapture experiments in experimental huts. Efficacy was significantly lower with all the LLINs tested; however, the roof of PermaNet 3.0 induced significantly higher mosquito mortality (50.4%) compared to Olyset Plus (25.9%) and Interceptor G2 (21.6%) LLINs. The efficacy of the alternative delivery methods was short-lived with mortality decreasing below 50% within 2 months in residual activity bioassays. None of the products tested appeared superior to the powder treatments. Further research is therefore required to identify suitable insecticide delivery options in EaveTube for malaria vector control.

Indexed as

AnophelesInsecticidesInsecticide-Treated BednetsMalariaMosquito ControlPyrethrinsAnimalsInsecticide ResistanceMosquito VectorsNitrilesPowdersRandomized Controlled Trials as TopiccyfluthrinInsecticidesNitrilesPowdersPyrethrins

Identifiers

PMID36964136
PMCPMC10039065
OpenAlexW4360857179

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read114
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.