Evidence map›Paper›PMID 36963505›Full record

ArticlePeptides2023

Peripheral vs. core body temperature as hypocretin/orexin neurons degenerate: Exercise mitigates increased heat loss.

Yu Sun, Ryan K Tisdale, Akira Yamashita, Thomas S Kilduff

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Peptides, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Yu SunBiosciences Division, SRI International, 333 Ravenswood Ave, Menlo Park, CA 94025, USA. Electronic address: yu.sun@sri.com.
Ryan K TisdaleBiosciences Division, SRI International, 333 Ravenswood Ave, Menlo Park, CA 94025, USA.
Akira YamashitaBiosciences Division, SRI International, 333 Ravenswood Ave, Menlo Park, CA 94025, USA; Department of Physiology, Kagoshima University Graduate School of Medical and Dental Science, Kagoshima 890-8544, Japan.
Thomas S KilduffBiosciences Division, SRI International, 333 Ravenswood Ave, Menlo Park, CA 94025, USA.
SRI International · USKagoshima University · JP

Funding

TAAR1-Alzheimers SupplementR01NS103529 · NINDS · SRI INTERNATIONAL · PI KILDUFF, THOMAS S · 2018 to 2022
$3.8M
U.S.-Japan BRCP Supplement to "The Tuberal Hypothalamus and Arousal State Control"R01NS098813 · NINDS · SRI INTERNATIONAL · PI KILDUFF, THOMAS S · 2016 to 2020
$3.3M
NINDS NIH HHS R01 NS098813NINDS NIH HHS R01 NS103529
6 · The paper itself

Abstract

Hypocretins/Orexins (Hcrt/Ox) are hypothalamic neuropeptides implicated in diverse functions, including body temperature regulation through modulation of sympathetic vasoconstrictor tone. In the current study, we measured subcutaneous (T

Indexed as

CataplexyNarcolepsyAnimalsBody TemperatureBody Temperature RegulationMiceMice, TransgenicNeuronsOrexinsOrexinsActivityBody temperatureHypocretinNarcolepsyOrexinSympathetic vasoconstrictionThermogenesis

Identifiers

PMID36963505
PMCPMC10337601
OpenAlexW4353055894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.