Evidence map›Paper›PMID 36963096›Full record

ArticlePLOS global public health2023

Genomic epidemiology of SARS-CoV-2 during the first four waves in Mozambique.

Nalia Ismael, Stephanie van Wyk, Houriiyah Tegally, Jennifer Giandhari, James Emmanuel San, Monika Moir, Sureshnee Pillay, Christian Utpatel, Lavanya Singh, Yeshnee Naidoo and 20 more

Full text read
In one paragraph

Article in PLOS global public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Nalia IsmaelInstituto Nacional de Saúde (INS), Marracuene, Mozambique.ORCID https://orcid.org/0000-0003-1793-9471
Stephanie van WykCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Houriiyah TegallyCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Jennifer GiandhariCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
James Emmanuel SanCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Monika MoirCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0003-1095-1910
Sureshnee PillayCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Christian UtpatelMolecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany.
Lavanya SinghCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0002-1726-4454
Yeshnee NaidooCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Upasana RamphalCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0002-2441-3868
Nédio MabundaInstituto Nacional de Saúde (INS), Marracuene, Mozambique.
Nuro AbílioInstituto Nacional de Saúde (INS), Marracuene, Mozambique.ORCID https://orcid.org/0000-0001-9760-7455
Paulo ArnaldoInstituto Nacional de Saúde (INS), Marracuene, Mozambique.
Joicymara XavierCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Daniel Gyamfi AmoakoCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service, Johannesburg, South Africa.
Josie EverattCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-0373-2093
Yajna RamphalCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Arisha MaharajCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0002-7136-3533
Leonardo de AraujoMolecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany.
Ugochukwu J AnyanejiCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Derek TshiabuilaCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Sofia ViegasInstituto Nacional de Saúde (INS), Marracuene, Mozambique.ORCID https://orcid.org/0000-0002-8575-0657
Richard LessellsCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.
Susan EngelbrechtDivision of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Eduardo GudoInstituto Nacional de Saúde (INS), Marracuene, Mozambique.
Ilesh JaniInstituto Nacional de Saúde (INS), Marracuene, Mozambique.ORCID https://orcid.org/0000-0002-6880-6655
Stefan NiemannMolecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany.
Eduan WilkinsonCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0002-2503-9441
Túlio de OliveiraCentre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch, South Africa.

Funding

University of Washington Arboviral Research Network (UWARN)U01AI151698 · NIAID · UNIVERSITY OF WASHINGTON · PI Michael Gale, PETER MACGARR RABINOWITZ · 2020 to 2026
$13.3M
Role of Data Streams In Informing Infection Dynamics in Africa- INFORM AfricaU54TW012041 · FIC · INSTITUTE OF HUMAN VIROLOGY · PI Alash'le G. Abimiku, Tulio de Paiva Nazareth Andrade De Oliveira · 2021 to 2026
$6.9M
Pitt-Mozambique Training Program (Pitt-MozHRTP) in SARS-CoV-2, Cardiovascular Disease, and Diabetes in People with HIVD43TW011827 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Lee H Harrison, JEAN BISIMWA NACHEGA · 2022 to 2026
$1.2M
FIC NIH HHS D43 TW011827FIC NIH HHS U54 TW012041NIAID NIH HHS U01 AI151698
6 · The paper itself

Abstract

Mozambique reported the first case of coronavirus disease 2019 (COVID-19) in March 2020 and it has since spread to all provinces in the country. To investigate the introductions and spread of SARS-CoV-2 in Mozambique, 1 142 whole genome sequences sampled within Mozambique were phylogenetically analyzed against a globally representative set, reflecting the first 25 months of the epidemic. The epidemic in the country was marked by four waves of infection, the first associated with B.1 ancestral lineages, while the Beta, Delta, and Omicron Variants of Concern (VOCs) were responsible for most infections and deaths during the second, third, and fourth waves. Large-scale viral exchanges occurred during the latter three waves and were largely attributed to southern African origins. Not only did the country remain vulnerable to the introductions of new variants but these variants continued to evolve within the borders of the country. Due to the Mozambican health system already under constraint, and paucity of data in Mozambique, there is a need to continue to strengthen and support genomic surveillance in the country as VOCs and Variants of interests (VOIs) are often reported from the southern African region.

Identifiers

PMID36963096
PMCPMC10021167

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read13
identifiers read5
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.