Evidence map›Paper›PMID 36962959›Full record

ArticlePLOS global public health2023

Fentanyl-driven acceleration of racial, gender and geographical disparities in drug overdose deaths in the United States.

Maria R D'Orsogna, Lucas Böttcher, Tom Chou

Open access · goldFull text read
In one paragraph

Article in PLOS global public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

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  18. Racial/ethnic inequality in homelessness and drug overdose deaths in US States.Social psychiatry and psychiatric epidemiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Maria R D'OrsognaDepartment of Computational Medicine, University of California at Los Angeles, Los Angeles, California, United States of America.ORCID https://orcid.org/0000-0003-2828-9523
Lucas BöttcherDepartment of Computational Science and Philosophy, Frankfurt School of Finance and Management, Frankfurt am Main, Germany.ORCID https://orcid.org/0000-0003-1700-1897
Tom ChouDepartment of Computational Medicine, University of California at Los Angeles, Los Angeles, California, United States of America.ORCID https://orcid.org/0000-0003-0785-6349
California State University, Northridge · USFrankfurt School of Finance & Management · DEUniversity of California, Los Angeles · US

Funding

Tracking clonal dynamics during hematopoiesis: mechanistic insight via modeling and data analysisR01HL146552 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHOU, TOM · 2019 to 2022
$907k
NHLBI NIH HHS R01 HL146552
6 · The paper itself

Abstract

We examine trends in drug overdose deaths by race, gender, and geography in the United States during the period 2013-2020. Race and gender specific crude rates were extracted from the final National Vital Statistics System multiple cause-of-death mortality files for several jurisdictions and used to calculate the male-to-female ratios of crude rates between 2013 and 2020. We established 2013-2019 temporal trends for four major drug types: psychostimulants with addiction potential (T43.6, such as methamphetamines); heroin (T40.1); natural and semi-synthetic opioids (T40.2, such as those contained in prescription pain-killers); synthetic opioids (T40.4, such as fentanyl and its derivatives) through a quadratic regression and determined whether changes in the pandemic year 2020 were statistically significant. We also identified which race, gender and states were most impacted by drug overdose deaths. Nationwide, the year 2020 saw statistically significant increases in overdose deaths from all drug categories except heroin, surpassing predictions based on 2013-2019 trends. Crude rates for Black individuals of both genders surpassed those for White individuals for fentanyl and psychostimulants in 2018, creating a gap that widened through 2020. In some regions, mortality among White persons decreased while overdose deaths for Black persons kept rising. The largest 2020 mortality statistic is for Black males in the District of Columbia, with a record 134 overdose deaths per 100,000 due to fentanyl, 9.4 times more than the fatality rate among White males. Male overdose crude rates in 2020 remain larger than those of females for all drug categories except in Idaho, Utah and Arkansas where crude rates of overdose deaths by natural and semisynthetic opioids for females exceeded those of males. Drug prevention, mitigation and no-harm strategies should include racial, geographical and gender-specific efforts, to better identify and serve at-risk groups.

Identifiers

PMID36962959
PMCPMC10032521
OpenAlexW4353042389

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read38
identifiers read6
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.