Evidence map›Paper›PMID 36962933›Full record

ArticlePLOS global public health2023

Substance use and other correlates of HIV infection among transwomen and men who have sex with men in Perú: Implications for targeted HIV prevention strategies for transwomen.

Elena Cyrus, Javier R Lama, Jorge Sanchez, Daniell S Sullivan, Segundo Leon, Manuel V Villaran, Panagiotis Vagenas, David Vu, Makella Coudray, Frederick L Altice

Open access · goldFull text read
In one paragraph

Article in PLOS global public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Elena CyrusDepartment of Population Health Sciences, College of Medicine, University of Central Florida, Orlando, FL, United States of America.
Javier R LamaAssociación Civil Impacta Salud y Educación (IMPACTA), Lima, Perú.ORCID https://orcid.org/0000-0002-4983-5725
Jorge SanchezCentro de Investigaciones Tecnológicas, Biomédicas y Medioambientales, Universidad Nacional Mayor de San Marcos, Lima, Peru.
Daniell S SullivanCollege of Medicine, Univeristy of Central Florida, Orlando, FL, United States of America.ORCID https://orcid.org/0000-0001-7868-0040
Segundo LeonSan Juan Bautista Privada, Lima, Perú.
Manuel V VillaranVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, United States of America.
Panagiotis VagenasBerkeley Research Development Office, University of California Berkeley, Berkeley, CA, United States of America.ORCID https://orcid.org/0000-0003-2107-0377
David VuCollege of Medicine, Univeristy of Central Florida, Orlando, FL, United States of America.
Makella CoudrayDepartment of Population Health Sciences, College of Medicine, University of Central Florida, Orlando, FL, United States of America.ORCID https://orcid.org/0000-0002-5906-3220
Frederick L AlticeDepartment of Global Health, Yale School of Public Health, New Haven, CT, United States of America.
University of Central Florida · USAsociación Civil Impacta Salud y Educación · PEFred Hutch Cancer Center · USNational University of San Marcos · PEUniversidad Privada San Juan Bautista · PEUniversity of California, Berkeley · US

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
Global Health Fellows and Scholars Research TrainingR25TW009338 · FIC · UNIVERSITY OF CALIFORNIA BERKELEY · PI BARRY, MICHELE, KO, ALBERT ICKSANG · 2012 to 2016
$5.2M
To Reach Unrestricted Services for Transgender Women (TRUST)R00DA046311 · NIDA · UNIVERSITY OF CENTRAL FLORIDA · PI CYRUS, ELENA · 2020 to 2022
$747k
To Reach Unrestricted Services for Transgender Women (TRUST)K99DA046311 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI CYRUS, ELENA · 2018 to 2019
$339k
FIC NIH HHS D43 TW010540FIC NIH HHS R25 TW009338NIAAA NIH HHS L30 AA027051NIDA NIH HHS K99 DA046311NIDA NIH HHS R00 DA046311
6 · The paper itself

Abstract

Characterization of HIV risk factors among transwomen and men who have sex with men (MSM) should be assessed separately and independently. However, due to several constraints, these populations continue to be conflated in clinical research and data. There are limited datasets globally powered to make such comparisons. The study aimed to use one of the largest surveys of transwomen and MSM in Latin America to determine differences in HIV risk and related correlates between the two populations. Secondary data analysis was completed using a cross-sectional biobehavioral survey of 4413 MSM and 714 transwomen living in Perú. Chi Square analysis of selected HIV correlates was conducted to examine differences between transwomen and MSM. Additionally, stratified binary logistic regression was used to split data for further comparative analyses of correlates associated with transwomen and MSM separately. HIV prevalence among transwomen was two-fold greater than among MSM (14.9% vs. 7.0%, p<0.001). Transwomen had a higher prevalence of most HIV risk factors assessed, including presence of alcohol dependence (16.4% vs. 19.0%; p < .001) and drug use in the past 3 months (17.0% vs. 14.9%). MSM were more likely to use marijuana (68.0% vs. 50.0%, p < .001), and transwomen were more likely to engage in inhaled cocaine use (70.0% vs. 51.1%, p < .001). The regression exposed differences in correlates driving sub-epidemics in transwomen vs. MSM, with a trend of substance use increasing HIV risk for transwomen only. Transwomen were more likely to be HIV-infected and had different risk factors from MSM. Targeted prevention strategies are needed for transwomen that are at highest risk. Additionally, further research is needed to determine if these observations in Perú regarding substance use patterns and the role of substance use in HIV risk relate to other trans populations globally.

Identifiers

PMID36962933
PMCPMC10022005
OpenAlexW4315709382

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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identifiers read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.