ArticlePLOS global public health2022
Toward a conceptual framework of the acceptability of tuberculosis treatment in children using a theory generative approach.
Article in PLOS global public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Acceptability of a Dolutegravir Oral Dispersible Film in Term Neonates Born to Mothers Living With HIV.Journal of the International AIDS Society · 2026Trial
- An exploratory, qualitative study of treatment preferences among participants in a TB therapeutic trial.IJTLD open · 2026Article
- Article
- Article
- "Six months is a lot of time to lie": Anticipated stigma, disclosure and treatment preferences among participants in a tuberculosis therapeutic trial.Research square · 2025Article
- Acceptability of 100-mg moxifloxacin in children with rifampicin-resistant TB in three high-burden countries.IJTLD open · 2025Article
- Acceptability of a clofazimine tablet in children with rifampicin-resistant TB in three high-burden countries.IJTLD open · 2025Article
- Children's preferences among six novel moxifloxacin and linezolid-dispersible tablet formulations.IJTLD open · 2025Article
- Acceptability of a 250 mg levofloxacin formulation in children receiving TB preventive treatment.IJTLD open · 2025Article
- Children and providers' perspectives on once-weekly rifapentine and isoniazid TB preventive therapy.IJTLD open · 2025Article
- Children, caregivers and health workers' perceptions and experiences of the XTEMP-R tool to improve tuberculosis treatment.PLOS global public health · 2025Article
- Including the voice of children <15-years-old in paediatric global health research.Current tropical medicine reports · 2024Article
- A conceptual framework on determinants of the integrated tuberculosis control model implementation in China.Frontiers in medicine · 2024Article
- A public health development intervention between acceptability and feasibility: descriptive-interpretive discussion of an example.The Pan African medical journal · 2024Article
- Holistic acceptability of an adult levofloxacin formulation in children and adolescents on a tuberculosis preventive treatment trial.PLOS global public health · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
To describe an early-stage holistic framework towards evaluating factors that impact the overall acceptability of TB treatment along the TB care cascade in children. We developed a conceptual framework utilising a theory generative approach. Domains were developed through review of existing definitions and analysis of existing qualitative data undertaken in acceptability studies of TB treatment in children. Clarity of domain definitions was achieved through iterative refinement among the research team. Three domains, each comprising several dimensions, were identified to holistically evaluate treatment acceptability: (1) usability, which involves the alignment between the requirements of treatment use and caregivers' and children's ability to integrate TB treatment into their everyday routines, (2) receptivity, which describes the end-user's perception and expectations of treatment and its actual use, and (3) integration, which describes the relationship between available health services and caregivers/children's capacity to make use of those services. Our framework addresses the gaps in current research which do not account for the influence of caregivers' and children's contexts on TB treatment uptake and overall acceptability. This approach may support the development of more standard, holistic measures to improve TB treatment delivery and experiences and future research in children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.