Evidence map›Paper›PMID 36962586›Full record

ArticlePLOS global public health2022

Machine learning with routine electronic medical record data to identify people at high risk of disengagement from HIV care in Tanzania.

Carolyn A Fahey, Linqing Wei, Prosper F Njau, Siraji Shabani, Sylvester Kwilasa, Werner Maokola, Laura Packel, Zeyu Zheng, Jingshen Wang, Sandra I McCoy

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Article in PLOS global public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Machine learning to improve HIV screening using routine data in Kenya.Journal of the International AIDS Society · 2025
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  12. Observational
  13. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carolyn A FaheyDepartment of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, United States of America.ORCID https://orcid.org/0000-0001-9865-2397
Linqing WeiDivision of Biostatistics, School of Public Health, University of California, Berkeley, California, United States of America.ORCID https://orcid.org/0000-0003-3504-4436
Prosper F NjauMinistry of Health, Dodoma, Tanzania.ORCID https://orcid.org/0000-0002-6351-9489
Siraji ShabaniMinistry of Health, Dodoma, Tanzania.ORCID https://orcid.org/0000-0003-4357-4971
Sylvester KwilasaMinistry of Health, Dodoma, Tanzania.
Werner MaokolaMinistry of Health, Dodoma, Tanzania.
Laura PackelDivision of Epidemiology, School of Public Health, University of California, Berkeley, California, United States of America.ORCID https://orcid.org/0000-0002-8186-5246
Zeyu ZhengDepartment of Industrial Engineering and Operations Research, University of California, Berkeley, California, United States of America.ORCID https://orcid.org/0000-0001-5653-152X
Jingshen WangDivision of Biostatistics, School of Public Health, University of California, Berkeley, California, United States of America.ORCID https://orcid.org/0000-0002-1432-3834
Sandra I McCoyDivision of Epidemiology, School of Public Health, University of California, Berkeley, California, United States of America.ORCID https://orcid.org/0000-0002-4764-9195

Funding

Strengthening the continuity of HIV care in Tanzania with economic supportR01MH125746 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI SABASABA, AMON NKWABI, WANG, JINGSHEN · 2021 to 2025
$3.3M
Optimizing the efficiency and implementation of cash transfers to improve adherenceto antiretroviral therapyR01MH112432 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI MCCOY, SANDRA I · 2017 to 2021
$2.9M
NIMH NIH HHS R01 MH112432NIMH NIH HHS R01 MH125746
6 · The paper itself

Abstract

Machine learning methods for health care delivery optimization have the potential to improve retention in HIV care, a critical target of global efforts to end the epidemic. However, these methods have not been widely applied to medical record data in low- and middle-income countries. We used an ensemble decision tree approach to predict risk of disengagement from HIV care (missing an appointment by ≥28 days) in Tanzania. Our approach used routine electronic medical records (EMR) from the time of antiretroviral therapy (ART) initiation through 24 months of follow-up for 178 adults (63% female). We compared prediction accuracy when using EMR-based predictors alone and in combination with sociodemographic survey data collected by a research study. Models that included only EMR-based indicators and incorporated changes across past clinical visits achieved a mean accuracy of 75.2% for predicting risk of disengagement in the next 6 months, with a mean sensitivity of 54.7% for targeting the 30% highest-risk individuals. Additionally including survey-based predictors only modestly improved model performance. The most important variables for prediction were time-varying EMR indicators including changes in treatment status, body weight, and WHO clinical stage. Machine learning methods applied to existing EMR data in resource-constrained settings can predict individuals' future risk of disengagement from HIV care, potentially enabling better targeting and efficiency of interventions to promote retention in care.

Identifiers

PMID36962586
PMCPMC10021592

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identifiers read5
Read underepoch 390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.