ArticlePLOS global public health2022
COVID-19 vaccine hesitancy and its determinants among sub-Saharan African adolescents.
Article in PLOS global public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Equitable access to COVID-19 vaccines in Botswana: a scoping review.Frontiers in health services · 2025Pooled it
- Pooled it
- Predictors of COVID-19 vaccination status among youth in eThekwini, South Africa: results from the AYAZAZI RIGHTS study.Global health action · 2026Article
- Coverage and determinants of COVID-19 vaccination among 36 555 Nigerian women of childbearing age: a mixed-effects analysis of nationally representative data.BMJ public health · 2026Article
- Strategies to promote COVID-19 vaccination in Northern Ghana: a qualitative study of stakeholders' perspectives.BMC public health · 2025Article
- Article
- Perceptions, attitudes, practices, and factors associated with COVID-19 vaccination among travelers in the Democratic Republic of the Congo.Tropical diseases, travel medicine and vaccines · 2025Article
- Global Systematic Scoping Review of Adolescent Factors Associated With COVID-19 Vaccine Hesitancy.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Factors shaping Covid-19 vaccine acceptability among young people in South Africa and Nigeria: An exploratory qualitative study.PLOS global public health · 2025Article
- Determinants of COVID-19 vaccine uptake among persons with disabilities in three selected districts of Zambia.PLOS global public health · 2025Article
- Understanding the perceptions of risks versus the benefits of COVID-19 vaccinations in Manyara, Tanzania.Journal of public health in Africa · 2025Article
- Disparities in anti-SARS-CoV-2 reactivity according to vaccines administered in the era of omicron in Cameroon: Lessons for future outbreak response.PLOS global public health · 2025Article
- Understanding the socio-ecological determinants of COVID-19 vaccine uptake: A cross-sectional study of post-COVID-19 Tanzania.Journal of public health in Africa · 2025Article
- Amplifying youth voices: young people's recommendations for policy and practice to enhance vaccine acceptability.BMC health services research · 2024Article
- Vaccine hesitancy in adolescents regarding COVID-19 vaccination: A literature review.Vaccine: X · 2024Review
- Article
- Corona virus vaccine hesitancy among higher education students in Adama City, Oromia, Ethiopia.Frontiers in public health · 2024Article
- Article
- Vaccine inequity: a threat to Africa's recovery from COVID-19.Tropical medicine and health · 2023Review
- Factors associated with COVID-19 vaccine uptake among people with type 2 diabetes in Kenya and Tanzania: a mixed-methods study.BMJ open · 2023Article
Corrections and comments
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Authors and funding
27 authors at 13 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
COVID-19 vaccine hesitancy among adolescents poses a challenge to the global effort to control the pandemic. This multi-country survey aimed to assess the prevalence and determinants of COVID-19 vaccine hesitancy among adolescents in sub-Saharan Africa between July and December 2021. The survey was conducted using computer-assisted telephone interviewing among adolescents in five sub-Saharan African countries, Burkina Faso, Ethiopia, Ghana, Nigeria, and Tanzania. A rural area and an urban area were included in each country (except Ghana, which only had a rural area), with approximately 300 adolescents in each area and 2662 in total. Sociodemographic characteristics and perceptions and attitudes on COVID-19 vaccines were measured. Vaccine hesitancy was defined as definitely not getting vaccinated or being undecided on whether to get vaccinated if a COVID-19 vaccine were available. Log-binomial models were used to calculate the adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs) for associations between potential determinants and COVID-19 vaccine hesitancy. The percentage of COVID-19 vaccine hesitancy was 14% in rural Kersa, 23% in rural Ibadan, 31% in rural Nouna, 32% in urban Ouagadougou, 37% in urban Addis Ababa, 48% in rural Kintampo, 65% in urban Lagos, 76% in urban Dar es Salaam, and 88% in rural Dodoma. Perceived low necessity, concerns about vaccine safety, and concerns about vaccine effectiveness were the leading reasons for hesitancy. Healthcare workers, parents or family members, and schoolteachers had the greatest impacts on vaccine willingness. Perceived lack of safety (aPR: 3.52; 95% CI: 3.00, 4.13) and lack of effectiveness (aPR: 3.46; 95% CI: 2.97, 4.03) were associated with greater vaccine hesitancy. The prevalence of COVID-19 vaccine hesitancy among adolescents is alarmingly high across the five sub-Saharan African countries, especially in Tanzania. COVID-19 vaccination campaigns among sub-Saharan African adolescents should address their concerns and misconceptions about vaccine safety and effectiveness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.