Evidence map›Paper›PMID 36962202›Full record

ArticlePLOS global public health2022

Alcohol reduction outcomes following brief counseling among adults with HIV in Zambia: A sequential mixed methods study.

Mah Asombang, Anna Helova, Jenala Chipungu, Anjali Sharma, Gilles Wandeler, Jeremy C Kane, Janet M Turan, Helen Smith, Michael J Vinikoor, for IeDEA Southern Africa

Open access · goldFull text read
In one paragraph

Article in PLOS global public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Mah AsombangCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.ORCID https://orcid.org/0000-0002-7455-4255
Anna HelovaSchool of Public Health, University of Alabama at Birmingham, Birmingham, AL, United States of America.ORCID https://orcid.org/0000-0002-2177-756X
Jenala ChipunguCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.
Anjali SharmaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.ORCID https://orcid.org/0000-0002-8189-0732
Gilles WandelerDepartment of Infectious Diseases and Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Jeremy C KaneColumbia University Mailman School of Public Health, New York City, NY, United States of America.ORCID https://orcid.org/0000-0002-6598-3840
Janet M TuranSchool of Public Health, University of Alabama at Birmingham, Birmingham, AL, United States of America.ORCID https://orcid.org/0000-0002-7802-6206
Helen SmithBradford Institute for Health Research, Bradford, United Kingdom.ORCID https://orcid.org/0000-0002-6252-3793
Michael J VinikoorCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.ORCID https://orcid.org/0000-0002-3862-7795
for IeDEA Southern Africa
Centre for Infectious Disease Research in Zambia · ZMUniversity of Alabama at Birmingham · USColumbia University · USUniversity of Bern · CH

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul A. Goepfert · 1988 to 2026
$84.1M
Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
Zambia Alabama HIV Alcohol Comorbidities Program (ZAMBAMA)P01AA029540 · NIAAA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MURRAY, LAURA KAY · 2021 to 2025
$5.7M
Improving measurement of alcohol consumption among HIV-affected youth in sub-Saharan Africa: evaluation and implementation of biomarkersK01AA026523 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KANE, JEREMY CALVIN · 2020 to 2024
$881k
Impact of antiretroviral therapy on liver fibrosis in Zambian HIV/HBV patientsK01TW009998 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VINIKOOR, MICHAEL JEFFREY · 2014 to 2017
$526k
FIC NIH HHS K01 TW009998NIAAA NIH HHS K01 AA026523NIAAA NIH HHS P01 AA029540NIAID NIH HHS P30 AI027767NIAID NIH HHS U01 AI069924
6 · The paper itself

Abstract

Data from sub-Saharan Africa on the impact of alcohol on the HIV epidemic in sub-Saharan Africa is limited. In this region, it is not well understood how people with HIV (PLWHA) respond to alcohol reduction counseling while they are linked to HIV clinical care. We conducted an explanatory sequential mixed-methods study to understand patterns of alcohol use among adults (18+ years) within a prospective HIV cohort at two urban public-sector clinics in Zambia. At antiretroviral therapy (ART) start and one year later, we measured alcohol use with Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) and those reporting any alcohol use were provided brief counseling. We conducted focus groups at 1 year with participants who had any alcohol use and 20 in-depth interviews among the subgroup with unhealthy use pre-ART and who either reduced or did not reduce their use by 1 year to moderate levels or abstinence. Focus group Discussions (FGDs) (n = 2) were also held with HIV clinic staff. Qualitative data were analyzed using thematic analysis. The data obtained from 693 participants was analyzed (median age 34 years, 45% men), it revealed that unhealthy alcohol use (AUDIT-C >3 for men; >2 for women) was reported among 280 (40.4%) at baseline and 205 (29.6%) at 1 year on ART. Reduction from unhealthy to moderate use or abstinence was more common with older age, female, non-smoking, and at Clinic B (all P<0.05). Qualitative data revealed ineffective alcohol support at clinics, social pressures in the community to consume alcohol, and unaddressed drivers of alcohol use including poverty, poor health status, depression, and HIV stigma. Healthcare workers reported a lack of training in alcohol screening and treatment, which led to mixed messages provided to patients ('reduce to safe levels' versus 'abstain'). In summary, interventions to reduce unhealthy alcohol use are needed within HIV clinics in Zambia as a substantial population have persistent unhealthy use despite current HIV clinical care. A better understanding is needed regarding the implementation challenges related to screening for unhealthy alcohol use integrated with HIV services.

Identifiers

PMID36962202
PMCPMC10021288
OpenAlexW4281489881

What OpenQuestion holds

Textfull text, public
LicenceCC0
measurements read29
identifiers read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.