Evidence map›Paper›PMID 36962173›Full record

ArticlePLOS global public health2022

Enhanced Integration of TB Services in Reproductive Maternal Newborn and Child Health (RMNCH) Settings in Eswatini.

Kieran Hartsough, Chloe A Teasdale, Siphesihle Shongwe, Amanda Geller, Eduarda Pimentel De Gusmao, Phumzile Dlamini, Arnold Mafukidze, Munyaradzi Pasipamire, Trong Ao, Caroline Ryan and 3 more

Open access · goldFull text read
In one paragraph

Article in PLOS global public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Kieran HartsoughICAP-Columbia University, Mailman School of Public Health, New York, NY, United States of America.ORCID https://orcid.org/0000-0001-6172-1870
Chloe A TeasdaleCUNY Graduate School of Public Health & Health Policy, Department of Epidemiology & Biostatistics, New York, NY, United States of America.ORCID https://orcid.org/0000-0001-9165-8972
Siphesihle ShongweICAP-Columbia University, Mailman School of Public Health, Mbabane, Eswatini.
Amanda GellerUS Centers for Disease Control and Prevention (CDC), Division of Global HIV & TB, Atlanta, GA, United States of America.
Eduarda Pimentel De GusmaoICAP-Columbia University, Mailman School of Public Health, Maputo, Mozambique.ORCID https://orcid.org/0000-0002-7225-3096
Phumzile DlaminiCenter for Global Health Practice and Impact, Georgetown University, Mbabane, Eswatini.ORCID https://orcid.org/0000-0002-0167-0634
Arnold MafukidzeCenter for Global Health Practice and Impact, Georgetown University, Mbabane, Eswatini.
Munyaradzi PasipamireCDC-Eswatini, Division of Global HIV & TB, Mbabane, Eswatini.ORCID https://orcid.org/0000-0002-7409-6995
Trong AoCDC-Eswatini, Division of Global HIV & TB, Mbabane, Eswatini.ORCID https://orcid.org/0000-0002-0775-5188
Caroline RyanCDC-Eswatini, Division of Global HIV & TB, Mbabane, Eswatini.
Surbhi ModiUS Centers for Disease Control and Prevention (CDC), Division of Global HIV & TB, Atlanta, GA, United States of America.ORCID https://orcid.org/0000-0003-2143-672X
Elaine J AbramsICAP-Columbia University, Mailman School of Public Health, New York, NY, United States of America.
Andrea A HowardICAP-Columbia University, Mailman School of Public Health, New York, NY, United States of America.ORCID https://orcid.org/0000-0003-3248-1307
Columbia University · USCenters for Disease Control and Prevention · USGeorgetown University · USEswatini Economic Policy Analysis and Research Centre · SZThe Graduate Center, CUNY · US

Funding

CGH CDC HHS U2G GH000994
6 · The paper itself

Abstract

Tuberculosis (TB) primarily affects women during their reproductive years and contributes to maternal mortality and poor pregnancy outcomes. For pregnant women living with HIV (WLHIV), TB is the leading cause of non-obstetric maternal mortality, and pregnant WLHIV with TB are at increased risk of transmitting both TB and HIV to their infants. TB diagnosis among pregnant women, particularly WLHIV, remains challenging, and TB preventive treatment (TPT) coverage among pregnant WLHIV is limited. This project aimed to strengthen integrated TB and reproductive, maternal, neonatal and child health (RMNCH) services in Eswatini to improve screening and treatment for TB disease, TPT uptake and completion among women receiving RMNCH services. The project was conducted from April-December 2017 at four health facilities in Eswatini and introduced enhanced monitoring tools and on-site technical support in RMNCH services. We present data on TB case finding among women, and TPT coverage and completion among eligible WLHIV. A questionnaire (S1 Appendix) measured healthcare provider perspectives on the project after three months of project implementation, including feasibility of scaling-up integrated TB and RMNCH services. A total of 5,724 women (HIV-negative or WLHIV) were screened for active TB disease while attending RMNCH services; 53 (0.9%) were identified with presumptive TB, of whom 37 (70%) were evaluated for TB disease and 6 (0.1% of those screened) were diagnosed with TB. Among 1,950 WLHIV who screened negative for TB, 848 (43%) initiated TPT and 462 (54%) completed. Forty-three healthcare providers completed the questionnaire, and overall were highly supportive of integrated TB and RMNCH services. Integration of TB/HIV services in RMNCH settings was feasible and ensured high TB screening coverage among women of reproductive age, however, symptom screening identified few TB cases, and further studies should explore various screening algorithms and diagnostics that optimize case finding in this population. Interventions should focus on working with healthcare providers and patients to improve TPT initiation and completion rates.

Identifiers

PMID36962173
PMCPMC10021747
OpenAlexW4224218198

What OpenQuestion holds

Textfull text, public
LicenceCC0
measurements read78
identifiers read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.