Evidence map›Paper›PMID 36962066›Full record

ArticlePLOS global public health2022

Knowledge barriers in a national symptomatic-COVID-19 testing programme.

Mark S Graham, Anna May, Thomas Varsavsky, Carole H Sudre, Benjamin Murray, Kerstin Kläser, Michela Antonelli, Liane S Canas, Erika Molteni, Marc Modat and 14 more

Full text read
In one paragraph

Article in PLOS global public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Trends in Testing for SARS-CoV-2 Among Healthcare Workers in a Canadian Cohort Study During the COVID-19 Pandemic, June 2020 to November 2023.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  5. Article
  6. Article
  7. PCR testing of traced contacts for SARS-CoV-2 in England, January to July 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  8. Article
  9. SARS-CoV-2 self-test uptake and factors associated with self-testing during Omicron BA.1 and BA.2 waves in France, January to May 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Mark S GrahamSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-4170-1095
Anna MayZoe Global Limited, London, United Kingdom.
Thomas VarsavskySchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-8624-8116
Carole H SudreSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0001-5753-428X
Benjamin MurraySchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-2413-923X
Kerstin KläserSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-5230-6939
Michela AntonelliSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-3005-4523
Liane S CanasSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-2553-1284
Erika MolteniSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0001-7773-8140
Marc ModatSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-5277-8530
M Jorge CardosoSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0003-1284-2558
David A DrewClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States of America.ORCID https://orcid.org/0000-0002-8813-0816
Long H NguyenClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States of America.ORCID https://orcid.org/0000-0002-5436-4219
Benjamin RaderComputational Epidemiology Lab, Boston Children's Hospital, Boston, MA, United States of America.ORCID https://orcid.org/0000-0002-6095-0193
Christina HuZoe Global Limited, London, United Kingdom.ORCID https://orcid.org/0000-0002-3586-3506
Joan CapdevilaZoe Global Limited, London, United Kingdom.
Alexander HammersSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.ORCID https://orcid.org/0000-0001-9530-4848
Andrew T ChanClinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States of America.ORCID https://orcid.org/0000-0001-7284-6767
Jonathan WolfZoe Global Limited, London, United Kingdom.ORCID https://orcid.org/0000-0002-0530-2257
John S BrownsteinComputational Epidemiology Lab, Boston Children's Hospital, Boston, MA, United States of America.
Tim D SpectorDepartment of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Sebastien OurselinSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.
Claire J StevesDepartment of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Christina M AstleyComputational Epidemiology Lab, Boston Children's Hospital, Boston, MA, United States of America.ORCID https://orcid.org/0000-0002-5063-8470

Funding

Seasonal and Viral Determinants of Type 1 Diabetes Onset, Remission, and Glycemic ControlK23DK120899 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI ASTLEY, CHRISTINA M. · 2019 to 2021
$682k
EPA EP-W-17-011NIDDK NIH HHS K23 DK120899Wellcome Trust
6 · The paper itself

Abstract

Symptomatic testing programmes are crucial to the COVID-19 pandemic response. We sought to examine United Kingdom (UK) testing rates amongst individuals with test-qualifying symptoms, and factors associated with not testing. We analysed a cohort of untested symptomatic app users (N = 1,237), nested in the Zoe COVID Symptom Study (Zoe, N = 4,394,948); and symptomatic respondents who wanted, but did not have a test (N = 1,956), drawn from a University of Maryland survey administered to Facebook users (The Global COVID-19 Trends and Impact Survey [CTIS], N = 775,746). The proportion tested among individuals with incident test-qualifying symptoms rose from ~20% to ~75% from April to December 2020 in Zoe. Testing was lower with one vs more symptoms (72.9% vs 84.6% p<0.001), or short vs long symptom duration (69.9% vs 85.4% p<0.001). 40.4% of survey respondents did not identify all three test-qualifying symptoms. Symptom identification decreased for every decade older (OR = 0.908 [95% CI 0.883-0.933]). Amongst symptomatic UMD-CTIS respondents who wanted but did not have a test, not knowing where to go was the most cited factor (32.4%); this increased for each decade older (OR = 1.207 [1.129-1.292]) and for every 4-years fewer in education (OR = 0.685 [0.599-0.783]). Despite current UK messaging on COVID-19 testing, there is a knowledge gap about when and where to test, and this may be contributing to the ~25% testing gap. Risk factors, including older age and less education, highlight potential opportunities to tailor public health messages. The testing gap may be ever larger in countries that do not have extensive, free testing, as the UK does.

Identifiers

PMID36962066
PMCPMC10022193

What OpenQuestion holds

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LicenceCC BY
measurements read210
identifiers read8
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.