Evidence map›Paper›PMID 36961907›Full record

ArticleScience immunology2023

The transcription factor Mef2d regulates B:T synapse-dependent GC-T

Ye-Ji Kim, Jeein Oh, Soohan Jung, Chan Johng Kim, Jinyong Choi, Yoon Kyung Jeon, Hyun Jik Kim, Ji-Won Kim, Chang-Hee Suh, Yoontae Lee and 3 more

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. The Role of MEF2 in Scar Formation and Angiogenesis.Journal of cosmetic dermatology · 2026
    Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Ye-Ji KimDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0001-7155-9635
Jeein OhDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0002-7075-7653
Soohan JungDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0003-3572-1126
Chan Johng KimDepartment of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Jinyong ChoiDepartment of Microbiology, Department of Biomedicine & Health Sciences, College of Medicine, Catholic University of Korea, Seoul, Korea.ORCID 0000-0003-2474-2837
Yoon Kyung JeonDepartment of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0001-8466-9681
Hyun Jik KimDepartment of Otorhinolaryngology, Seoul National University Hospital, Seoul, Korea.ORCID 0000-0001-8631-928X
Ji-Won KimDepartment of Rheumatology, Ajou University School of Medicine, Gyeonggi-do, Korea.ORCID 0000-0002-2827-0884
Chang-Hee SuhDepartment of Rheumatology, Ajou University School of Medicine, Gyeonggi-do, Korea.ORCID 0000-0001-6156-393X
Yoontae LeeDepartment of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Korea.ORCID 0000-0002-6810-3087
Sin-Hyeog ImDepartment of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Korea.ORCID 0000-0002-3173-1856
Shane CrottyCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, CA, USA.ORCID 0000-0002-6484-6262
Youn Soo ChoiDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0001-6291-6178
Seoul National University · KRPohang University of Science and Technology · KRAjou University · KRSeoul National University Hospital · KRCatholic University of Korea · KRLa Jolla Institute for Immunology · US

Funding

Transcription factor regulation of CD4 and CD8 T cell effector and memory differentiation and functionP01AI145815 · NIAID · UNIVERSITY OF FLORIDA · PI PIPKIN, MATTHEW EUGENE · 2020 to 2024
$11.0M
Tfh and SAP and T cell help to B cellsR01AI072543 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROTTY, SHANE P · 2008 to 2018
$4.6M
NIAID NIH HHS P01 AI145815NIAID NIH HHS R01 AI072543
6 · The paper itself

Abstract

Communication between CD4 T cells and cognate B cells is key for the former to fully mature into germinal center-T follicular helper (GC-T

Indexed as

Immunity, HumoralT-Lymphocytes, Helper-InducerCell DifferentiationHumansInterleukin-21MEF2 Transcription FactorsTranscription FactorsInterleukin-21MEF2D protein, humanMEF2 Transcription FactorsTranscription Factors

Identifiers

PMID36961907
PMCPMC10311795
OpenAlexW4360827997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.