Evidence map›Paper›PMID 36961451›Full record

ArticleThe British journal of radiology2023

Changes in pancreatic exocrine function, fat and fibrosis in diabetes mellitus: analysis using MR imaging.

Kazuya Yasokawa, Akihiko Kanki, Hiroki Nakamura, Hidemitsu Sotozono, Yu Ueda, Kiyoka Maeba, Ayumu Kido, Atsushi Higaki, Minoru Hayashida, Akira Yamamoto and 1 more

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Kazuya YasokawaDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.ORCID 0000-0001-9733-2586
Akihiko KankiDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Hiroki NakamuraDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Hidemitsu SotozonoDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Yu UedaMR Clinical Science, Philips Japan, Tokyo, Japan.
Kiyoka MaebaDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Ayumu KidoDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Atsushi HigakiDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Minoru HayashidaDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Akira YamamotoDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Tsutomu TamadaDepartment of Diagnostic Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
Kawasaki Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the relationships between hemoglobin A1c (HbA1c) levels with exocrine pancreatic function using cine-dynamic magnetic resonance cholangiopancreatography (MRCP) and the pancreatic parenchyma using fat-suppressed T1 mapping and the proton density fat fraction (PDFF).

methodsPatients who underwent 3T-MRI and HbA1c measurement were retrospectively recruited. MRI included cine-dynamic MRCP with a spatially selective inversion-recovery (SS-IR) pulse, fat-suppressed Look-Locker T1 mapping and multiecho 3D Dixon-based PDFF mapping. The pancreatic exocrine secretion grade on cine-dynamic MRCP, T1 values, and PDFF were analyzed in non-diabetic (

resultsPDFF was weakly correlation with HbA1c (ρ = 0.30,

conclusionPancreatic exocrine function, T1, and FF showed no correlation with HbA1c. Pancreatic T1 and fat fraction is increased in patients with Type 2 diabetes mellitus. ADVANCES IN KNOWLEDGE: This study demonstrates unaffected exocrine function in pre-diabetes and diabetes and confirms that pancreatic parenchymal T1 and FF are increased in patients with diabetes.

Indexed as

Diabetes Mellitus, Type 2Prediabetic StateFibrosisGlycated HemoglobinHumansMagnetic Resonance ImagingRetrospective StudiesGlycated Hemoglobin

Identifiers

PMID36961451
PMCPMC10161908
OpenAlexW4360809366

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.