ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023
A Sleep-Specific Midbrain Target for Sevoflurane Anesthesia.
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Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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0cells of the map it votes in
22citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
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Who cites it
22 citing papers in PubMed, 29 citations in OpenAlex.
- Effect of lidocaine on acute pain after modified radical mastectomy: a secondary analysis of a randomized trial.Frontiers in medicine · 2026Trial
- 40-Hz Light Stimulation and Emergence Delirium Incidence After Sevoflurane Anesthesia in Children: A Randomized Clinical Trial.JAMA pediatrics · 2025Trial
- TRIM14 Knockdown is Associated with Attenuated Sevoflurane-Induced Ferroptosis and Mitochondrial Dysfunction in Hippocampal Neurons.Neurotoxicity research · 2026Article
- Parallel cholinergic circuit in oculomotor nucleus to control eye movements and REM sleep.Nature communications · 2026Article
- Anesthetic State-Dependent Bidirectional Control of States of Consciousness via Heterogeneous Medial Septum to Ventral Tegmental Area Circuits under Sevoflurane in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Edinger-Westphal Neurons Contribute to Emergence from Desflurane and Sevoflurane Anesthesia in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- A Brainstem-Thalamic-Cortex Glutamatergic Neuron Pathway Modulates Propofol Anesthesia.Drug design, development and therapy · 2026Article
- Immunoreactivity and distribution of Fos in the mouse brain following diverse general anesthetics.Scientific reports · 2025Article
- Effects of volatile and intravenous anesthetics on postoperative cognitive dysfunction: a mechanistic review.Journal of anesthesia · 2025Review
- Blood-brain barrier-penetrating Angiopep-2/Sirtuin 1 nanoparticles rescue sevoflurane neurotoxicity through multi-omics identified necroptosis pathways.Journal of nanobiotechnology · 2025Article
- Morroniside ameliorates sevoflurane anesthesia-induced cognitive dysfunction in aged mice through modulating the TLR4/NF-κB pathway.Biomolecules & biomedicine · 2025Article
- Propofol Promotes Anesthesia Through the Activation of Centrally-Projecting Edinger-Westphal Nucleus Urocortin 1-Positive Neurons.Neuroscience bulletin · 2025Article
- Activation of CaMKIICell biology and toxicology · 2025Article
- [Activation of astrocytes in the dorsomedial hypothalamus accelerates sevoflurane anesthesia emergence in mice].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Sevoflurane Alleviates Cardiomyocyte Ferroptosis via Ubiquitin-Specific Protease 7/Phosphatase and Tensin Homolog Modulation.Drug design, development and therapy · 2025Article
- Isolated theta waves originating from the midline thalamus trigger memory reactivation during NREM sleep in mice.Nature communications · 2024Article
- A hypothalamus-lateral periaqueductal gray GABAergic neural projection facilitates arousal following sevoflurane anesthesia in mice.CNS neuroscience & therapeutics · 2024Article
- Article
- A Common Neuronal Ensemble in the Lateral Habenula Regulates Ciprofol Anesthesia in Mice.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Anesthetic spindles serve as EEG markers of the depth variations in anesthesia induced by multifarious general anesthetics in mouse experiments.Frontiers in pharmacology · 2024Article
Corrections and comments
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Authors and funding
22 authors at 2 institutions in 1 country.
Tingting YiDepartment of Anesthesiology, Second Affiliated Hospital, Third Military Medical University, Chongqing, 400037, China.
Na WangDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Jing HuangDepartment of Anesthesiology, Second Affiliated Hospital, Third Military Medical University, Chongqing, 400037, China.
Yaling WangDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Shuancheng RenDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Yiwen HuDepartment of Anesthesiology, Second Affiliated Hospital, Third Military Medical University, Chongqing, 400037, China.
Jianxia XiaDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Yixiang LiaoDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Xin LiDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Fenlan LuoDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Qin OuyangSchool of Pharmacy, Third Military Medical University, Chongqing, 400038, China.
Yu LiDepartment of Anesthesiology, Second Affiliated Hospital, Third Military Medical University, Chongqing, 400037, China.
Ziyi ZhengDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Qin XiaoDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Rong RenSleep Medicine Center, Department of Respiratory and Critical Care Medicine, Mental Health Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Zhongxiang YaoDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Xiangdong TangSleep Medicine Center, Department of Respiratory and Critical Care Medicine, Mental Health Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Yanjiang WangDepartment of Neurology, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.
Xiaowei ChenBrain Research Center, Collaborative Innovation Center for Brain Science, Third Military Medical University, Chongqing, 400038, China.
Chao HeDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.
Hong LiDepartment of Anesthesiology, Second Affiliated Hospital, Third Military Medical University, Chongqing, 400037, China.
Zhian HuDepartment of Physiology, Third Military Medical University, Chongqing, 400038, China.ORCID 0000-0002-4439-537X
Army Medical University · CNSichuan University · CN
Funding
Innovative Research Groups of the National Natural Science Foundation of China 31921003National Major Project of China Science and Technology Innovation 2030 for Brain Science and Brain-Inspired Technology 2021ZD0203201National Major Project of China Science and Technology Innovation 2030 for Brain Science and Brain-Inspired Technology 2021ZD0203401National Natural Science Foundation of China 31970945National Natural Science Foundation of China 32022030National Natural Science Foundation of China 82171265
Abstract
Sevoflurane has been the most widely used inhaled anesthetics with a favorable recovery profile; however, the precise mechanisms underlying its anesthetic action are still not completely understood. Here the authors show that sevoflurane activates a cluster of urocortin 1 (UCN1
Indexed as
AnesthesiaMesencephalonSevofluraneSleepUrocortinsSevofluraneUrocortinsEdinger-Westphal nucleusgeneral anesthesiagrowth hormone secretagogue receptorsevofluranesleep
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.