Evidence map›Paper›PMID 36960998›Full record

ArticleTomography (Ann Arbor, Mich.)2023

Variant Sciatic Nerve Anatomy in Relation to the Piriformis Muscle on Magnetic Resonance Neurography: A Potential Etiology for Extraspinal Sciatica.

Upasana Upadhyay Bharadwaj, Vanja Varenika, William Carson, Javier Villanueva-Meyer, Simon Ammanuel, Matthew Bucknor, Nathaniel M Robbins, Vanja Douglas, Cynthia T Chin

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Upasana Upadhyay BharadwajDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-4710-809X
Vanja VarenikaRadNet Northern California, RadNet Imaging Centers, San Francisco, CA 90815, USA.
William CarsonSouthwest Medical Imaging, Scottsdale, AZ 85258, USA.
Javier Villanueva-MeyerDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA.
Simon AmmanuelDepartment of Neurological Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Matthew BucknorDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA.
Nathaniel M RobbinsDepartment of Neurology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.ORCID 0000-0002-1884-8275
Vanja DouglasDepartment of Neurology, UCSF Weill Institute for Neurosciences, San Francisco, CA 94143, USA.
Cynthia T ChinDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA.
University of California, San Francisco · USDartmouth College · USImaging Center · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the prevalence and clinical implications of variant sciatic nerve anatomy in relation to the piriformis muscle on magnetic resonance neurography (MRN), in patients with lumbosacral neuropathic symptoms. MATERIALS AND

methodsIn this retrospective single-center study, 254 sciatic nerves, from 127 patients with clinical and imaging findings compatible with extra-spinal sciatica on MRN between 2003 and 2013, were evaluated for the presence and type of variant sciatic nerves, split sciatic nerve, abnormal T2-signal hyperintensity, asymmetric piriformis size and increased nerve caliber, and summarized using descriptive statistics. Two-tailed chi-square tests were performed to compare the anatomical variant type and clinical symptoms between imaging and clinical characteristics.

resultsSixty-four variant sciatic nerves were identified with an equal number of right and left variants. Bilateral variants were noted in 15 cases. Abnormal T2-signal hyperintensity was seen significantly more often in variant compared to conventional anatomy (40/64 vs. 82/190;

conclusionVariant sciatic nerve anatomy, in relation to the piriformis muscle, is frequently identified with MRN and is more likely to be associated with nerve signal changes and symptomatology.

Indexed as

SciaticaHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMuscle, SkeletalRetrospective StudiesSciatic NerveMRIneurogrampiriformissciatic nervevariant anatomy

Identifiers

PMID36960998
PMCPMC10037619
OpenAlexW4321495552

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read42
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.