ArticlePlant physiology2023
Paralog editing tunes rice stomatal density to maintain photosynthesis and improve drought tolerance.
Article in Plant physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Greater aperture counteracts effects of reduced stomatal density on water use efficiency: a case study on sugarcane and meta-analysis.Journal of experimental botany · 2024Pooled it
- Plant peptide hormones: three decades of discovery and emerging paradigms.Plant physiology · 2026Review
- Signaling by a tyrosine-sulfated peptide balances growth and osmotic stress response in rice.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Comprehensive Profiling of the RicePlants (Basel, Switzerland) · 2026Article
- The developing leaf of the wild grass Brachypodium distachyon at single-cell resolution.The Plant cell · 2026Article
- A Truncated WRKY Protein Enhances Drought Resistance in Wild Tomatoes Through the SlWRKY16-CIP2b-SlSYP121 Module.Plant biotechnology journal · 2026Article
- Brachypodium SPEECHLESS2 Promoter Drives Expression of a Synthetic EPF to Reduce Stomatal Density in Sugarcane Without Pleiotropic Effects.Plant biotechnology journal · 2026Article
- Engineered TnpB genome editors for plants and human cells identified by ribonucleoprotein mutational scanning.Nature biotechnology · 2026Article
- ERECTA-family receptor kinases: versatile regulators of plant developmental signaling.The Plant journal : for cell and molecular biology · 2026Review
- Stomata in-sight: Integrating live confocal microscopy with leaf gas exchange and environmental control.Plant physiology · 2025Article
- PagHB7/PagABF4-PagEPFL9 Module Regulates Stomatal Density and Drought Tolerance in Poplar.Plant biotechnology journal · 2025Article
- Unlocking grass leaf development: foundations for tunable cereal design.The New phytologist · 2025Review
- Plant hydraulic traits influencing crop production in water-limited environments.Plant physiology · 2025Review
- Mutational scanning of TnpB reveals latent activity for genome editing.bioRxiv : the preprint server for biology · 2025Article
- Smarter stomata: emergent technologies unlocking yield potential in a changing climate.AoB PLANTS · 2025Review
- Effect of Singlet Oxygen on the Stomatal and Cell Wall of Rice Seedling Under Different Stresses.International journal of molecular sciences · 2025Article
- Reduced stomatal density improves water-use efficiency in grapevine under climate scenarios of decreased water availability.Plant cell reports · 2025Article
- Translational insights into abiotic interactions: From Arabidopsis to crop plants.The Plant cell · 2025Review
- DSD1/ZmICEb regulates stomatal development and drought tolerance in maize.Journal of integrative plant biology · 2025Article
- Transcriptional gene network involved in drought stress response: application for crop breeding in the context of climate change.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 1 country.
Funding
Abstract
Rice (Oryza sativa) is of paramount importance for global nutrition, supplying at least 20% of global calories. However, water scarcity and increased drought severity are anticipated to reduce rice yields globally. We explored stomatal developmental genetics as a mechanism for improving drought resilience in rice while maintaining yield under climate stress. CRISPR/Cas9-mediated knockouts of the positive regulator of stomatal development STOMAGEN and its paralog EPIDERMAL PATTERNING FACTOR-LIKE10 (EPFL10) yielded lines with ∼25% and 80% of wild-type stomatal density, respectively. epfl10 lines with moderate reductions in stomatal density were able to conserve water to similar extents as stomagen lines but did not suffer from the concomitant reductions in stomatal conductance, carbon assimilation, or thermoregulation observed in stomagen knockouts. Moderate reductions in stomatal density achieved by editing EPFL10 present a climate-adaptive approach for safeguarding yield in rice. Editing the paralog of STOMAGEN in other species may provide a means for tuning stomatal density in agriculturally important crops beyond rice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.