Evidence map›Paper›PMID 36960318›Full record

ArticleJID innovations : skin science from molecules to population health2023

Development and Narrow Validation of Computer Vision Approach to Facilitate Assessment of Change in Pigmented Cutaneous Lesions.

William F Maguire, Paul H Haley, Catherine M Dietz, Mike Hoffelder, Clara S Brandt, Robin Joyce, Georgia Fitzgerald, Christopher Minnier, Cindy Sander, Laura K Ferris and 6 more

Open access · goldAbstract read
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

William F MaguireDivision of Hematology/Oncology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Paul H HaleyComputer Vision Group, Veytel, Pittsburgh, Pennsylvania, USA.
Catherine M DietzComputer Vision Group, Veytel, Pittsburgh, Pennsylvania, USA.
Mike HoffelderComputer Vision Group, Veytel, Pittsburgh, Pennsylvania, USA.
Clara S BrandtComputer Vision Group, Veytel, Pittsburgh, Pennsylvania, USA.
Robin JoyceComputer Vision Group, Veytel, Pittsburgh, Pennsylvania, USA.
Georgia FitzgeraldComputer Vision Group, Veytel, Pittsburgh, Pennsylvania, USA.
Christopher MinnierUPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
Cindy SanderUPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
Laura K FerrisDepartment of Dermatology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Gyorgy ParaghDepartment of Dermatology, Roswell Park Comprehensive Cancer Institute, Buffalo, New York, USA.
Joshua ArbesmanCleveland Clinic, Cleveland, Ohio, USA.
Hong WangSchool of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Kevin J MitchellComputer Vision Group, Veytel, Pittsburgh, Pennsylvania, USA.
Ellen K HughesComputer Vision Group, Veytel, Pittsburgh, Pennsylvania, USA.
John M KirkwoodDivision of Hematology/Oncology, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · USMount Holyoke College · USUPMC Hillman Cancer Center · USCleveland Clinic · USRoswell Park Comprehensive Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The documentation of the change in the number and appearance of pigmented cutaneous lesions over time is critical to the early detection of skin cancers and may provide preliminary signals of efficacy in early-phase therapeutic prevention trials for melanoma. Despite substantial progress in computer-aided diagnosis of melanoma, automated methods to assess the evolution of lesions are relatively undeveloped. This report describes the development and narrow validation of mathematical algorithms to register nevi between sequential digital photographs of large areas of skin and to align images for improved detection and quantification of changes. Serial posterior truncal photographs from a pre-existing database were processed and analyzed by the software, and the results were evaluated by a panel of clinicians using a separate Extensible Markup Language‒based application. The software had a high sensitivity for the detection of cutaneous lesions as small as 2 mm. The software registered lesions accurately, with occasional errors at the edges of the images. In one pilot study with 17 patients, the use of the software enabled clinicians to identify new and/or enlarged lesions in 3‒11 additional patients versus the unregistered images. Automated quantification of size change performed similarly to that of human raters. These results support the further development and broader validation of this technique.

Indexed as

CI, confidence interval

Identifiers

PMID36960318
PMCPMC10030255
OpenAlexW4313829838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.