Evidence map›Paper›PMID 36960316›Full record

ArticleJAC-antimicrobial resistance2023

Antibiotic consumption trends in Ghana: analysis of six-years pharmacy issue data from a secondary healthcare facility.

Appiah-Korang Labi, Bridget S Kartey, George Kwesi Hedidor, Benjamin Demah Nuertey, Elsie Kodjoe, Leslie No Vanderpuije, Noah Obeng-Nkrumah

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Article in JAC-antimicrobial resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Appiah-Korang LabiDepartment of Medical Microbiology, University of Ghana Medical School, University of Ghana, Korle-Bu, Accra, Ghana.ORCID https://orcid.org/0000-0001-7276-7057
Bridget S KarteyPharmacy Department, Eastern Regional Hospital, Koforidua, Ghana.
George Kwesi HedidorLife Course Cluster, WHO Ghana Country Office, No. 7 Ameda Street, Roman Ridge, Accra, Ghana.
Benjamin Demah NuerteyLife Course Cluster, WHO Ghana Country Office, No. 7 Ameda Street, Roman Ridge, Accra, Ghana.
Elsie KodjoeLife Course Cluster, WHO Ghana Country Office, No. 7 Ameda Street, Roman Ridge, Accra, Ghana.
Leslie No VanderpuijePharmacy Unit, Ghana Health Service Eastern Regional Health Directorate, Koforidua, Ghana.
Noah Obeng-NkrumahDepartment of Medical Laboratory Science, School of Biomedical and Allied Health Sciences, University of Ghana, Accra, Ghana.ORCID https://orcid.org/0000-0002-1797-822X

Funding

World Health Organization 001
6 · The paper itself

Abstract

Background: Surveillance of hospital antibiotic consumption provides data to inform corrective action and for monitoring antimicrobial stewardship activities. This study described antibiotic consumption patterns from 2016 through 2021 at a secondary healthcare facility in Ghana. Methods: Using the WHO methodology for surveillance of antimicrobial consumption in hospitals, we analysed a 6-year pharmacy issue data at the Eastern Regional Hospital. We report on the defined daily dose (DDD) per 100 patients, types of antibiotics consumed according to Anatomic Therapeutic Classification (ATC), WHO AWaRe classification; trends in antibiotic consumption and expenditure per DDD of antibiotics consumed. Results: Over the period, the mean (±standard deviation) antibiotic consumption rate was 256.7 ± 33 DDD/100 patients per year. A linear regression model showed an insignificant decreasing trend in antibiotic consumption (coefficient for time -0.561; Conclusion: This study showed a sturdy rate of antibiotic consumption over the 6-year period with a year-on-year decrease in the Access-to-Watch antibiotic ratio. Data from pharmacy drug issues offer an opportunity to conduct antibiotic consumption surveillance at the hospital and national level in Ghana.

Identifiers

PMID36960316
PMCPMC10027653

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.