Evidence map›Paper›PMID 36960290›Full record

ArticleFrontiers in microbiology2023

The

Simone Marini, Christina Boucher, Noelle Noyes, Mattia Prosperi

Full text read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. OCTOPUS: Disk-based, Multiplatform, Mobile-friendly Metagenomics Classifier.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simone MariniDepartment of Epidemiology, University of Florida, Gainesville, FL, United States.
Christina BoucherDepartment of Computer and Information Science and Engineering, University of Florida, Gainesville, FL, United States.
Noelle NoyesDepartment of Veterinary Population Medicine, University of Minnesota, St. Paul, MN, United States.
Mattia ProsperiDepartment of Epidemiology, University of Florida, Gainesville, FL, United States.

Funding

Forecasting trajectories of HIV transmission networks with a novel phylodynamic and deep learning frameworkR01AI145552 · NIAID · UNIVERSITY OF FLORIDA · PI Simone Marini, Mattia Prosperi · 2020 to 2026
$3.6M
Developing Computational Methods for Surveillance of Antimicrobial Resistant AgentsR01AI141810 · NIAID · UNIVERSITY OF FLORIDA · PI BOUCHER, CHRISTINA, PROSPERI, MATTIA · 2019 to 2023
$2.1M
NIAID NIH HHS R01 AI141810NIAID NIH HHS R01 AI145552
6 · The paper itself

Abstract

Characterization of antibiotic resistance genes (ARGs) from high-throughput sequencing data of metagenomics and cultured bacterial samples is a challenging task, with the need to account for both computational (e.g., string algorithms) and biological (e.g., gene transfers, rearrangements) aspects. Curated ARG databases exist together with assorted ARG classification approaches (e.g., database alignment, machine learning). Besides ARGs that naturally occur in bacterial strains or are acquired through mobile elements, there are chromosomal genes that can render a bacterium resistant to antibiotics through point mutations, i.e., ARG variants (ARGVs). While ARG repositories also collect ARGVs, there are only a few tools that are able to identify ARGVs from metagenomics and high throughput sequencing data, with a number of limitations (e.g., pre-assembly,

Indexed as

antibiotic resistancebioinformaticsgene variantshigh-throughput sequencingmetagenomicsstatistical learning

Identifiers

PMID36960290
PMCPMC10027697

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read5
measurements read33
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.