Evidence map›Paper›PMID 36960248›Full record

ArticleCureus2023

Rare Presentation of a Common Disease: Graves' Thyrotoxicosis Presented With Non-parathyroid Hypercalcemia and Jaundice.

Ibrahim Ajwah, Sameerah Alshehri, Fahad Alremthi, Nasser Alahmari

Open access · diamondFull text readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 4 countries.

Ibrahim AjwahDepartment of Endocrinology, Diabetes and Metabolism, King Abdulaziz Medical City, Ministry of the National Guard-Health Affairs, Riyadh, SAU.
Sameerah AlshehriDepartment of Endocrinology, Diabetes and Metabolism, King Abdulaziz Medical City, Ministry of the National Guard-Health Affairs, Riyadh, SAU.
Fahad AlremthiDepartment of Endocrinology, Diabetes and Metabolism, King Abdullah Hospital, Diabetes and Endocrine Center, Ministry of Health (MOH), Bisha, SAU.
Nasser AlahmariDepartment of Endocrinology, Diabetes and Metabolism, King Abdulaziz Medical City, Ministry of the National Guard-Health Affairs, Riyadh, SAU.
Ministry of Defence · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graves' disease (GD) is an autoimmune thyroid disease, which is considered the most common cause of primary hyperthyroidism. GD usually manifests with symptoms such as tremors, palpitations, heat intolerance, weight loss, and specific signs on physical examination (proptosis and pretibial myxedema). However, systemic involvement is also recognized, for example, hepatic involvement in patients with GD may range from asymptomatic laboratory findings of liver function derangement (either transaminases elevations or intrahepatic cholestasis) up to hepatic failure. We describe a rare case of Graves' thyrotoxicosis presenting with severe cholestasis and non-parathyroid hormone-related hypercalcemia. An extensive evaluation for hepatobiliary causes of cholestasis, including hepatic biopsy, was entirely negative. The patient was successfully treated with methimazole with subsequent clinical and biochemical improvement.

Indexed as

auto immunegraves´diseasehypercalcemiajaundiceparathyroid hormone (pth)

Identifiers

PMID36960248
PMCPMC10031658
OpenAlexW4321373654

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read17
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.