Evidence map›Paper›PMID 36960188›Full record

ArticleOncology letters2023

Status and prognostic value of immunological biomarkers of breast cancer.

Chisa Murazawa, Nozomi Hashimoto, Kana Kuraishi, Mutsumi Motoyama, Shin-Ichiro Hashimoto, Mayumi Ikeuchi, Shoko Norimura, Toru Matsunaga, Koji Teramoto, Reiji Haba and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Chisa MurazawaDepartment of Thoracic, Breast and Endocrine Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.
Nozomi HashimotoDepartment of Thoracic, Breast and Endocrine Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.
Kana KuraishiDepartment of Thoracic, Breast and Endocrine Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.
Mutsumi MotoyamaDepartment of Diagnostic Pathology, Kagawa University Hospital, Kagawa 761-0793, Japan.
Shin-Ichiro HashimotoDepartment of Thoracic, Breast and Endocrine Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.
Mayumi IkeuchiDepartment of Thoracic, Breast and Endocrine Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.
Shoko NorimuraDepartment of Surgery, Takamatsu Red Cross Hospital, Takamatsu, Kagawa 760-0017, Japan.
Toru MatsunagaDepartment of Diagnostic Pathology, Kagawa University Hospital, Kagawa 761-0793, Japan.
Koji TeramotoDepartment of Medical Oncology, Shiga University of Medical Science, Otsu, Shiga 520-2191, Japan.
Reiji HabaDepartment of Diagnostic Pathology, Kagawa University Hospital, Kagawa 761-0793, Japan.
Noriko AbeDepartment of Thoracic, Breast and Endocrine Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.
Toshiki YajimaDepartment of Thoracic, Breast and Endocrine Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.
Keiichi KontaniDepartment of Thoracic, Breast and Endocrine Surgery, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan.
Kagawa University · JPKagawa University Hospital · JPShiga University of Medical Science · JPTakamatsu Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune response to cancer serves an important role in disease progression and patient prognosis. For triple-negative breast cancer showing aggressive behavior, immunotherapy has a good efficacy because of the potent immunogenicity of this type of cancer. However, the dominant subtype, luminal human epidermal growth factor receptor-2 (HER2)-negative breast cancer, is less immunogenic. To determine whether luminal HER2-negative cancer reacts to the anticancer immune response, the present study analyzed the status and prognostic value of the principal immunological biomarkers of breast cancer, including tumor-infiltrating lymphocytes (TILs), CD8

Indexed as

biomarkerbreast cancerCD8+ T lymphocytesMHCPD-L1TILs

Identifiers

PMID36960188
PMCPMC10028224
OpenAlexW4323569679

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.