ArticleFrontiers in neuroscience2023
Alpha peak activity in resting-state EEG is associated with depressive score.
Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Electroencephalogram for the Diagnosis of Depression: A Systematic Review and Meta-Analysis of Diagnostic Test Accuracy.Brain topography · 2026Pooled it
- Resting-state EEG activity in depression: a systematic review and meta-analysis.NeuroImage. Clinical · 2026Pooled it
- Distinct origins of human low and high alpha rhythms revealed by simultaneous EEG-SEEG.Communications biology · 2026Article
- Toward Multi-Dimensional Depression Assessment: EEG-Based Machine Learning and Neurophysiological Interpretation for Diagnosis, Severity, and Cognitive Decline.Brain sciences · 2026Article
- Peak alpha frequency is associated with pain severity in Long COVID patients with new-onset chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- A data-centric and interpretable EEG framework for depression severity grading using SHAP-based insights.Journal of neuroengineering and rehabilitation · 2025Article
- Functional brain changes related to adverse childhood experiences and the presence of psychopathology.Discover mental health · 2025Article
- Estimating Chronological Age From the Electrical Activity of the Brain: How EEG-Age Can Be Used as a Marker of General Brain Functioning.Psychophysiology · 2025Article
- Effects of Manual Acupuncture Versus Sham Acupuncture in patients with Post-Stroke Depression: A Randomized Clinical Trial.Neurology and therapy · 2024Article
- Article
- Resting-State Alpha Activity in the Frontal and Occipital Lobes and Assessment of Cognitive Impairment in Depression Patients.Psychology research and behavior management · 2024Article
- Transcranial alternating current stimulation for the treatment of major depressive disorder: from basic mechanisms toward clinical applications.Frontiers in human neuroscience · 2023Review
- The effect of depression on the peak alpha frequency as a biomarker of pain sensitivity.Neurobiology of pain (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Depression is a serious psychiatric disorder characterized by prolonged sadness, loss of interest or pleasure. The dominant alpha peak activity in resting-state EEG is suggested to be an intrinsic neural marker for diagnosis of mental disorders. Methods: To investigate an association between alpha peak activity and depression severity, the present study recorded resting-state EEG (EGI 128 channels, off-line average reference, source reconstruction by a distributed inverse method with the sLORETA normalization, parcellation of 68 Desikan-Killiany regions) from 155 patients with depression (42 males, mean age 35 years) and acquired patients' scores of Self-Rating Depression Scales. We measured both the alpha peak amplitude that is more related to synchronous neural discharging and the alpha peak frequency that is more associated with brain metabolism. Results: The results showed that over widely distributed brain regions, individual patients' alpha peak amplitudes were negatively correlated with their depressive scores, and individual patients' alpha peak frequencies were positively correlated with their depressive scores. Discussion: These results reveal that alpha peak amplitude and frequency are associated with self-rating depressive score in different manners, and the finding suggests the potential of alpha peak activity in resting-state EEG acting as an important neural factor in evaluation of depression severity in supplement to diagnosis.
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