ArticleFrontiers in physiology2023
Splenic contraction and cardiovascular responses are augmented during apnea compared to rebreathing in humans.
Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Splenic contraction associated with sudden, transient hypotension and sympathoexcitation in humans.Experimental physiology · 2026Article
- Interindividual variability in static apnoea performance is partly explained by genetic factors.Experimental physiology · 2026Article
- Cardiovascular, respiratory and splenic responses to rebreathing and apnoea during exercise.Experimental physiology · 2026Article
- Advances in breath-hold diving research: a state-of-the-art review.European journal of applied physiology · 2026Review
- Apnoea as a novel method to improve exercise performance: A current state of the literature.Experimental physiology · 2025Review
- Time courses for pulmonary oxygen uptake and cardiovascular responses are similar during apnea in resting humans.Frontiers in physiology · 2025Article
- On the mechanisms of stress-induced human spleen contraction: training for a higher blood oxygen-carrying capacity.European journal of applied physiology · 2024Review
- Hemoglobin concentration and blood shift during dry static apnea in elite breath hold divers.Frontiers in physiology · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spleen contracts during apnea, releasing stored erythrocytes, thereby increasing systemic hemoglobin concentration (Hb). We compared apnea and rebreathing periods, of equal sub-maximal duration (mean 137 s; SD 30), in eighteen subjects to evaluate whether respiratory arrest or hypoxic and hypercapnic chemoreceptor stimulation is the primary elicitor of splenic contraction and cardiovascular responses during apnea. Spleen volume, Hb, cardiovascular variables, arterial (SaO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.