Evidence map›Paper›PMID 36960125›Full record

ArticleInternational journal of nanomedicine2023

A Novel Strategy for Liposomal Drug Separation in Plasma by TiO

Yue-Yang Yu, Mei Yuan, Wei-Jie Qin, Hai-Hong Bai, Hong-Zhuo Liu, Jin-Jing Che

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yue-Yang YuBeijing Institute of Pharmacology and Toxicology, State Key Laboratory of Toxicology and Medical Countermeasures, Beijing, People's Republic of China.
Mei YuanBeijing Institute of Pharmacology and Toxicology, State Key Laboratory of Toxicology and Medical Countermeasures, Beijing, People's Republic of China.
Wei-Jie QinState Key Laboratory of Proteomics, National Center for Protein Sciences, Beijing Institute of Lifeomics, Beijing, People's Republic of China.
Hai-Hong BaiPhase I Clinical Trial Center, Beijing Shijitan Hospital of Capital Medical University, Beijing, People's Republic of China.
Hong-Zhuo LiuWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, People's Republic of China.
Jin-Jing CheBeijing Institute of Pharmacology and Toxicology, State Key Laboratory of Toxicology and Medical Countermeasures, Beijing, People's Republic of China.
Shenyang Pharmaceutical University · CNBeijing Shijitan Hospital · CNState Key Laboratory of Proteomics

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Liposomes are nano-scale materials with a biofilm-like structure. They have excellent biocompatibility and are increasingly useful in drug delivery systems. However, the in vivo fate of liposomal drugs is still unclear because existing bioanalytical methods for quantitation of total and liposomal-encapsulated drugs have limits. A novel strategy for liposomal-encapsulated drug separation from plasma was developed via the specific coordinate binding interaction of TiO Methods: Liposomal-encapsulated docetaxel was separated from plasma by TiO Results: The encapsulated docetaxel had a concentration range of 15-4000 ng/mL from the plasma sample using a TiO Conclusion: TiO

Indexed as

LiposomesTandem Mass SpectrometryAnimalsChromatography, LiquidDocetaxelMicrospheresRatsTitaniumDocetaxelLiposomesTitaniumtitanium dioxidebioanalysiscoordinate bindingdocetaxel liposomesliposomal-encapsulated drugTiO2 microspheres

Identifiers

PMID36960125
PMCPMC10029972
OpenAlexW4327747721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.