Evidence map›Paper›PMID 36959987›Full record

ArticleEuroasian journal of hepato-gastroenterology

Frequency of

Shahid Rasool, Sofia Hanif, Aneeqa Ahmad, Umair Shafqat, Ahmad Nawaz Babar

Open access · diamondAbstract read
In one paragraph

Article in Euroasian journal of hepato-gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Shahid RasoolDepartment of Gastroenterology, University Medical and Dental College, Faisalabad, Punjab, Pakistan.ORCID https://orcid.org/0000-0002-8088-4445
Sofia HanifDepartment of Gastroenterology, Madina Teaching Hospital, Faisalabad, Punjab, Pakistan.
Aneeqa AhmadDepartment of Medicine, Allied Hospital Faisalabad, Faisalabad, Punjab, Pakistan.ORCID https://orcid.org/0000-0002-7263-6492
Umair ShafqatDepartment of Gastroenterology, Madina Teaching Hospital, Faisalabad, Punjab, Pakistan.ORCID https://orcid.org/0000-0002-2790-7345
Ahmad Nawaz BabarDepartment of Gastroenterology, Madina Teaching Hospital, Faisalabad, Punjab, Pakistan.ORCID https://orcid.org/0000-0001-8642-5613
University of Faisalabad · PKAllied Hospital · PKPunjab Medical College · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic hepatitis C (CHC) management has changed tremendously after direct-acting antivirals (DAAs) availability. Sustained virological response (SVR) has improved significantly, but one of the major concerns is the chances of Materials and methods: This prospective, interventional research was conducted from June 2017 to September 2020. All patients after antiviral therapy for CHC were followed with an ultrasound abdomen and α-fetoprotein, six monthly. Multiphasic computed tomography (CT) of the abdomen was performed in suspected cases. For quantitative variables, the mean and standard deviations were calculated, whereas the qualitative variables were analyzed by frequencies and percentages. Results: Among 180 patients, 110 were men and 70 were women with a mean age of 45.52 ± 11.71 years. One hundred and twenty-six patients were noncirrhotic, 38 had compensated cirrhosis while 16 had decompensated cirrhosis. One hundred and sixty-four (91.11%) patients achieved SVR, of which 22 (12.22%) patients developed new HCC during follow-up. Compensated cirrhosis group had 10 patients, the decompensated group had 12 patients, and the noncirrhotic group had no new HCC cases. Among patients with the new HCC, 12 achieved SVR. Conclusion: The risk of the development of HCC after antiviral treatment is highly significant among patients with liver cirrhosis. So, a strict surveillance strategy should be adopted in every cirrhotic patient following treatment with DAA agents even if they achieve SVR. Clinical significance: Chances of developing HCC are still significantly high even after achieving SVR with DAAs in patients with liver cirrhosis.Patients with liver cirrhosis should be under surveillance for HCC even after achieving SVR after DAAs treatment. How to cite this article: Rasool S, Hanif S, Ahmad A,

Indexed as

CirrhosisDirect acting antiviralHepatocellular carcinoma

Identifiers

PMID36959987
PMCPMC10028701
OpenAlexW4324086352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.