Evidence map›Paper›PMID 36959960›Full record

ArticleF&S reports2023

Morphometric assessment of blastocysts: relationship with the ongoing pregnancy rate.

Hiroki Utsuno, Tomoko Ishimaru, Miho Matsumoto, Chiharu Sasamori, Hikaru Takahashi, Hiroko Kimura, Shintaro Kamijo, Mitsutoshi Yamada, Mamoru Tanaka, Toshio Hamatani

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Article in F&S reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroki UtsunoClinical Laboratory, Keio University Hospital, Tokyo, Japan.
Tomoko IshimaruClinical Laboratory, Keio University Hospital, Tokyo, Japan.
Miho MatsumotoClinical Laboratory, Keio University Hospital, Tokyo, Japan.
Chiharu SasamoriClinical Laboratory, Keio University Hospital, Tokyo, Japan.
Hikaru TakahashiClinical Laboratory, Keio University Hospital, Tokyo, Japan.
Hiroko KimuraDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Shintaro KamijoDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Mitsutoshi YamadaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Mamoru TanakaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.
Toshio HamataniDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore a morphometric grading system for blastocysts that is associated with ongoing pregnancy. Design: Cross-sectional study. Setting: None. Patientss: All consecutive vitrified blastocysts at our center from July 2018 to November 2021 that were transferred in single blastocyst transfer cycles until January 2022. Interventions: None. Main Outcome Measures: The ongoing pregnancy rate after a single vitrified-warmed blastocyst transfer. Interobserver agreement on morphometric values among embryologists. Results: Three morphometric variables (blastocyst diameter, area of inner cell mass [ICM], and the estimated trophectoderm cell count) were used to evaluate the expansion, ICM, and trophectoderm morphology. During the study period, 585 blastocysts were involved in this study. Of the 3 morphometric variables, ICM area (per 500 μm Conclusions: Morphometric values of ICM and trophectoderm are promising predictors of pregnancy success. The high reproducibility suggests that the morphometric variables will contribute to identifying blastocysts with the highest developmental potential as well as those that will not result in a successful pregnancy.

Indexed as

Blastocyst morphologyinner cell massmorphometryongoing pregnancy ratetrophectoderm

Identifiers

PMID36959960
PMCPMC10028418

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