Evidence map›Paper›PMID 36959921›Full record

ArticleJournal of immunology research2023

The Potential Diagnostic Biomarkers for the IgG Subclass in Coal Workers' Pneumoconiosis.

Zhao-Guo Li, Bai-Cun Li, Zhi-Wei Li, Hui-Yuan Hu, Xia Ma, Hong Cao, Zhi-Hua Yu, Hua-Ping Dai, Jing Wang, Chen Wang

Open access · goldFull text read
In one paragraph

Article in Journal of immunology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Diagnostic potential of serum ACE and CBC inflammatory markers in silicosis in the ceramic workers.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zhao-Guo LiDepartment of Respiratory, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150086 Heilongjiang, China.
Bai-Cun LiInstitute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100730, China.
Zhi-Wei LiInstitute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100730, China.
Hui-Yuan HuInstitute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100730, China.
Xia MaDepartment of Pulmonary and Critical Care Medicine, General Hospital of Datong Coal Mine Group Co., Ltd, Datong 037000, China.
Hong CaoOccupational Disease Prevention and treatment Hospital of Datong Coal Mine Group Co., Ltd, Datong 037001, China.
Zhi-Hua YuOccupational Disease Prevention and treatment Hospital of Datong Coal Mine Group Co., Ltd, Datong 037001, China.
Hua-Ping Dai *Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, National Center for Respiratory Medicine, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, National Clinical Research Center for Respiratory Disease, Beijing 100029, China.ORCID https://orcid.org/0000-0003-1124-1582
Jing Wang *Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100730, China.ORCID https://orcid.org/0000-0003-2410-5408
Chen Wang *Department of Respiratory, The Second Affiliated Hospital of Harbin Medical University, Harbin, 150086 Heilongjiang, China.ORCID https://orcid.org/0000-0001-7857-5435
Chinese Academy of Medical Sciences & Peking Union Medical College · CNHarbin Medical University · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence suggests that exposure to coal dust increases immunoglobulin concentration. However, there is a paucity of data reporting immunoglobulin G (IgG) subclass in coal workers' pneumoconiosis (CWP). Therefore, this study intended to evaluate potential diagnostic biomarkers for the disease. CWP patients, dust-exposed workers without pneumoconiosis (DEW), and matched healthy controls (HCs) presented to the General Hospital of Datong Coal Mining Group and Occupational Disease Prevention and Treatment Hospital of Datong Coal Mining Group between May 2019 and September 2019 were recruited. The serum immunoglobulin concentration was determined by the multiplex immunoassay technique. Totally, 104 CWP patients, 109 DEWs, and 74 HCs were enrolled. Serum levels of IgG1, IgG2, IgM, and IgA were elevated in CWPs compared with those in DEWs and HCs (

Indexed as

AnthracosisOccupational ExposurePneumoconiosisBiomarkersCoalDustHumansImmunoglobulin AImmunoglobulin GImmunoglobulin MBiomarkersCoalDustImmunoglobulin AImmunoglobulin GImmunoglobulin M

Identifiers

PMID36959921
PMCPMC10030223
OpenAlexW4324295755

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read28
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.