Evidence map›Paper›PMID 36959870›Full record

ArticleTalanta open2023

Using low-cost disposable immunosensor based on flexible PET screen-printed electrode modified with carbon black and gold nanoparticles for sensitive detection of SARS-CoV-2.

Luís M C Ferreira, Isabela F Reis, Paulo R Martins, Luiz H Marcolino-Junior, Marcio F Bergamini, Jessica R Camargo, Bruno C Janegitz, Fernando C Vicentini

Open access · goldAbstract read
In one paragraph

Article in Talanta open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Luís M C FerreiraCenter of Nature Sciences, Federal University of São Carlos, Rod. Lauri Simões de Barros km 12, 18290-000, Buri, SP, Brazil.
Isabela F ReisCenter of Nature Sciences, Federal University of São Carlos, Rod. Lauri Simões de Barros km 12, 18290-000, Buri, SP, Brazil.
Paulo R MartinsInstitute of Chemistry, Federal University of Goiás, Av. Esperança, Goiania, GO 74690-900, Brazil.
Luiz H Marcolino-JuniorLaboratory of Electrochemical Sensors (LabSensE) - Department of Chemistry, Federal University of Paraná, 81.531-980, Curitiba, PR, Brazil.
Marcio F BergaminiLaboratory of Electrochemical Sensors (LabSensE) - Department of Chemistry, Federal University of Paraná, 81.531-980, Curitiba, PR, Brazil.
Jessica R CamargoDepartment of Nature Sciences, Mathematics and Education, Federal University of São Carlos, 13600-970, Araras, SP, Brazil.
Bruno C JanegitzDepartment of Nature Sciences, Mathematics and Education, Federal University of São Carlos, 13600-970, Araras, SP, Brazil.
Fernando C VicentiniCenter of Nature Sciences, Federal University of São Carlos, Rod. Lauri Simões de Barros km 12, 18290-000, Buri, SP, Brazil.
Universidade Federal de São Carlos · BRUniversidade Federal do Paraná · BRUniversidade Federal de Goiás · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To help meet the global demand for reliable and inexpensive COVID-19 testing and environmental analysis of SARS-CoV-2, the present work reports the development and application of a highly efficient disposable electrochemical immunosensor for the detection of SARS-CoV-2 in clinical and environmental matrices. The sensor developed is composed of a screen-printed electrode (SPE) array which was constructed using conductive carbon ink printed on polyethylene terephthalate (PET) substrate made from disposable soft drink bottles. The recognition site (Spike S1 Antibody (anti-SP Ab)) was covalently immobilized on the working electrode surface, which was effectively modified with carbon black (CB) and gold nanoparticles (AuNPs). The immunosensing material was subjected to a multi-technique characterization analysis using X-ray diffraction (XRD), transmission electron microscopy (TEM), and scanning electron microscopy (SEM) with elemental analysis via energy dispersive spectroscopy (EDS). The electrochemical characterization of the electrode surface and analytical measurements were performed using cyclic voltammetry (CV) and square-wave voltammetry (SWV). The immunosensor was easily applied for the conduct of rapid diagnoses or accurate quantitative environmental analyses by setting the incubation period to 10 min or 120 min. Under optimized conditions, the biosensor presented limits of detection (LODs) of 101 fg mL

Indexed as

Carbon blackElectrochemical immunosensorGold nanoparticlesLow-cost diagnosisPETSARS-CoV-2Screen-printed electrode

Identifiers

PMID36959870
PMCPMC9998283
OpenAlexW4323863285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.