Evidence map›Paper›PMID 36959655›Full record

Trial reportMalaria journal2023

Association between malaria and household air pollution interventions in a predominantly rural area of Ghana.

Kwaku Poku Asante, Blair J Wylie, Felix B Oppong, Ashlinn Quinn, Stephaney Gyaase, Alison G Lee, Kenneth Ayuurebobi Ae-Ngibise, Katrin Burkart, Ellen Abrafi Boamah-Kaali, Seyram Kaali and 4 more

Open access · goldFull text readRandomized Controlled Trial
In one paragraph

Trial report in Malaria journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 65% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Current update on malaria in pregnancy: a systematic review.Tropical diseases, travel medicine and vaccines · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 2 countries.

Kwaku Poku Asante *Kintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Bono East Region, Ghana. kwakupoku.asante@kintampo-hrc.org.
Blair J Wylie *Department of Obstetrics and Gynecology PH Building, Columbia University Medical Center, 16th Floor 622 West 168th Street, New York, NY, 10032, USA.
Felix B OppongKintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Bono East Region, Ghana.
Ashlinn QuinnBerkeley Air Monitoring Group, 1935 Addison St., Suite A, Berkeley, CA, 94704, USA.
Stephaney GyaaseKintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Bono East Region, Ghana.
Alison G LeeDivision of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kenneth Ayuurebobi Ae-NgibiseKintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Bono East Region, Ghana.
Katrin BurkartInstitute for Health Metrics and Evaluation, University of Washington, 2301 Fifth Ave., Seattle, WA, 98121, USA.
Ellen Abrafi Boamah-KaaliKintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Bono East Region, Ghana.
Seyram KaaliKintampo Health Research Centre, Research and Development Division, Ghana Health Service, Kintampo North Municipality, Bono East Region, Ghana.
Steven ChillrudLamont-Doherty Earth Observatory at Columbia University, Palisades, NY, USA.
Patrick L Kinney *Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA.
Seth Owusu-AgyeiInstitute of Health Research, University of Health and Allied Sciences, Ho, Ghana.
Darby Jack *Department of Environmental Health Sciences, Mailman School of Public Health at Columbia University, 722 W 168th Street, New York, NY, 10032, USA.
Kintampo Health Research Centre · GHBerkeley Air Monitoring Group (United States) · USBoston University · USColumbia University · USColumbia University Irving Medical Center · USIcahn School of Medicine at Mount Sinai · USLamont-Doherty Earth Observatory · USUniversity of Health and Allied Sciences · GHUniversity of Washington · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
6 · The paper itself

Abstract

backgroundThough anecdotal evidence suggests that smoke from HAP has a repellent effect on mosquitoes, very little work has been done to assess the effect of biomass smoke on malaria infection. The study, therefore, sought to investigate the hypothesis that interventions to reduce household biomass smoke may have an unintended consequence of increasing placental malaria or increase malaria infection in the first year of life.

methodsThis provides evidence from a randomized controlled trial among 1414 maternal-infant pairs in the Kintampo North and Kintampo South administrative areas of Ghana. Logistic regression was used to assess the association between study intervention assignment (LPG, Biolite or control) and placental malaria. Finally, an extended Cox model was used to assess the association between study interventions and all episodes of malaria parasitaemia in the first year of infant's life.

resultsThe prevalence of placental malaria was 24.6%. Out of this, 20.8% were acute infections, 18.7% chronic infections and 60.5% past infections. The study found no statistical significant association between the study interventions and all types of placental malaria (OR = 0.88; 95% CI 0.59-1.30). Of the 1165 infants, 44.6% experienced at least one episode of malaria parasitaemia in the first year of life. The incidence of first and/or only episode of malaria parasitaemia was however found to be similar among the study arms.

conclusionThe findings suggest that cookstove interventions for pregnant women and infants, when combined with additional malaria prevention strategies, do not lead to an increased risk of malaria among pregnant women and infants.

Indexed as

Air PollutionMalariaFemaleGhanaHumansInfantPlacentaPregnancySmokeSmoke

Identifiers

PMID36959655
PMCPMC10037900
OpenAlexW4360609954

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read33
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.