Evidence map›Paper›PMID 36959543›Full record

Trial reportBMC anesthesiology2023

Effects of pecto-intercostal fascial block combined with rectus sheath block for postoperative pain management after cardiac surgery: a randomized controlled trial.

Lu Wang, Luyang Jiang, Bailin Jiang, Ling Xin, Miao He, Wei Yang, Zhou Zhao, Yi Feng

Open access · goldFull text readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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  4. Superficial Parasternal Intercostal Plane Block and Full Sternotomy; A Randomized Trial.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lu WangDepartment of Anesthesiology, Peking University People's Hospital, 11 Xizhimen South Street, Beijing, 100044, China.
Luyang JiangDepartment of Anesthesiology, Peking University People's Hospital, 11 Xizhimen South Street, Beijing, 100044, China.
Bailin JiangDepartment of Anesthesiology, Peking University People's Hospital, 11 Xizhimen South Street, Beijing, 100044, China.
Ling XinDepartment of Anesthesiology, Peking University People's Hospital, 11 Xizhimen South Street, Beijing, 100044, China.
Miao HeDepartment of Anesthesiology, Peking University People's Hospital, 11 Xizhimen South Street, Beijing, 100044, China.
Wei YangDepartment of Cardiac Surgery, Peking University People's Hospital, Beijing, China.
Zhou ZhaoDepartment of Cardiac Surgery, Peking University People's Hospital, Beijing, China.
Yi FengDepartment of Anesthesiology, Peking University People's Hospital, 11 Xizhimen South Street, Beijing, 100044, China. doctor_yifeng@sina.com.
Peking University · CNPeking University People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPecto-intercostal fascial block (PIFB) provides analgesia for cardiac median sternotomy, but many patients complain of severe drainage pain that cannot be covered by PIFB. Rectus sheath block (RSB) has been attempted to solve this problem, but whether PIFB combined with RSB can achieve better analgesia is uncertain.

methodsThis was a single-center randomized controlled trial at Peking University People's Hospital from September 22, 2022 to December 21, 2022. Patients undergoing elective cardiac surgery with a median sternotomy were randomized at a 1:1 ratio to receive either bilateral PIFB and RSB (PIFB + RSB group) or PIFB (PIFB group). The primary outcome was intravenous opioid consumption within 24 h after surgery. Secondary outcomes included opioid consumption within 48 h, postoperative pain scores, time to extubation, and length of stay in the hospital. Interleukin (IL)-6, IL-10, and tumor necrosis factor (TNF)-α before and the first 24 h after surgery were measured.

resultsA total of 54 patients were analyzed (27 in each group). Intravenous opioid consumption within 24 h after surgery was 2.33 ± 1.77 mg in the PIFB + RSB group vs 3.81 ± 2.24 mg in the PIFB group (p = 0.010). Opioid consumption within 48 h after surgery was also reduced in the PIFB + RSB group (4.71 ± 2.71 mg vs 7.25 ± 3.76 mg, p = 0.006). There was no significant difference in pain scores, time to extubation, length of stay in hospital, or the levels of IL-6, IL-10 and TNF-α between the two groups.

conclusionsThe combination of PIFB and RSB reduced postoperative intravenous opioid consumption until 48 h after cardiac surgery.

trial registrationThis trial is registered at the Chinese Clinical Trial Registry ( www.chictr.org.cn , ChiCTR2200062017) on 19/07/2022.

Indexed as

Cardiac Surgical ProceduresNerve BlockAnalgesics, OpioidAnesthetics, LocalHumansInterleukin-10Interleukin-6Postoperative PainAnalgesics, OpioidAnesthetics, LocalInterleukin-10Interleukin-6AnalgesiaCardiac surgical proceduresNerve blockOpioid

Identifiers

PMID36959543
PMCPMC10035143
OpenAlexW4360613514

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read49
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.