Evidence map›Paper›PMID 36959516›Full record

ArticleArchives of microbiology2023

Paraprobiotics strains accelerate wound repair by stimulating re-epithelialization of NIH-3T3 cells, decreasing inflammatory response and oxidative stress.

Monique Michels, Emily Córneo, Luana Bezerra Gonçalves Rocha, Rodrigo Dias, Ana Paula Lorenzen Voytena, Marina Rossetto, Fernanda Ramlov, Felipe Dal-Pizzol, Gabriel Fernandes Alves Jesus

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In one paragraph

Article in Archives of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Monique MichelsGabbia Biotechnology, Barra Velha, Santa Catarina, Brazil. moniquemichels@hotmail.com.
Emily CórneoLaboratory of Experimental Pathophysiology-Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Luana Bezerra Gonçalves RochaLaboratory of Experimental Pathophysiology-Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Rodrigo DiasLaboratory of Experimental Pathophysiology-Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Ana Paula Lorenzen VoytenaGabbia Biotechnology, Barra Velha, Santa Catarina, Brazil.
Marina RossettoGabbia Biotechnology, Barra Velha, Santa Catarina, Brazil.
Fernanda RamlovGabbia Biotechnology, Barra Velha, Santa Catarina, Brazil.
Felipe Dal-PizzolLaboratory of Experimental Pathophysiology-Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Gabriel Fernandes Alves JesusGabbia Biotechnology, Barra Velha, Santa Catarina, Brazil.
Centro Universitário do Espírito Santo · BRBiotechnology Research Center · IRUniversidade do Vale do Itajaí · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico MONIQUE MICHELS - PDI
6 · The paper itself

Abstract

The present study aimed to evaluate the potential and specificity of the inflammatory and antioxidant response of Microbe-Associated Molecular Patterns (MAMPs) in NIH-3T3 fibroblast cells, as well as in the healing process of skin wounds. Cells (NIH-3T3) were cultivated in supplemented specific medium. NIH-3T3 cells were treated with MAMPs (Bifidobacterium lactis or Lactobacillus casei or Lactobacillus gasseri or Lactobacillus paracasei or Streptococcus thermophilus), at two concentrations and insulted with LPS or H

Indexed as

Hydrogen PeroxideRe-EpithelializationAnimalsAntioxidantsLipopolysaccharidesMiceNIH 3T3 CellsOxidative StressWound HealingAntioxidantsHydrogen PeroxideLipopolysaccharidesFibroblastInflammationMAMPsOxidative stressParaprobioticsScratch assay

Identifiers

PMID36959516
OpenAlexW4360810778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.