ArticleNature human behaviour2023
Neurons in human pre-supplementary motor area encode key computations for value-based choice.
Article in Nature human behaviour, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Population geometries in frontal cortex coordinate value-based decisions.bioRxiv : the preprint server for biology · 2026Article
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- The role of attention in multi attribute decision making.Nature communications · 2025Article
- Neural variability in the medial prefrontal cortex contributes to efficient adaptive behavior.Nature communications · 2025Article
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- Evidence accumulation in the pre-supplementary motor area and insula drives confidence and changes of mind.Nature communications · 2025Article
- Article
- Agency Modulation of Hippocampal Activity During Spatial Navigation.Research square · 2025Article
- Substantial Heritability Underlies Fairness Norm Adaptation Capability and its Neural Basis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Role for Left Dorsomedial Prefrontal Cortex in Self-Generated, but not Externally Cued, Language Production.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Free Will as Defined by the Constrained Disorder Principle: a Restricted, Mandatory, Personalized, Regulated Process for Decision-Making.Integrative psychological & behavioral science · 2024Review
- Beta and theta oscillations track effort and previous reward in the human basal ganglia and prefrontal cortex during decision making.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The neurocomputational link between defensive cardiac states and approach-avoidance arbitration under threat.Communications biology · 2024Article
- Encoding of Predictive Associations in Human Prefrontal and Medial Temporal Neurons During Pavlovian Appetitive Conditioning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Temporally organized representations of reward and risk in the human brain.Nature communications · 2024Article
- The Neural Correlates of Individual Differences in Reinforcement Learning during Pain Avoidance and Reward Seeking.eNeuro · 2024Article
- Beta and theta oscillations track effort and previous reward in human basal ganglia and prefrontal cortex during decision making.bioRxiv : the preprint server for biology · 2023Article
- Exploring the Impact of Smartphone Addiction on Risk Decision-Making Behavior among College Students Based on fNIRS Technology.Brain sciences · 2023Article
- Neurophysiological mechanisms of error monitoring in human and non-human primates.Nature reviews. Neuroscience · 2023Review
- Accounting for multiscale processing in adaptive real-world decision-making via the hippocampus.Frontiers in neuroscience · 2023Review
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5 authors.
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Abstract
Adaptive behaviour in real-world environments requires that choices integrate several variables, including the novelty of the options under consideration, their expected value and uncertainty in value estimation. Here, to probe how integration over decision variables occurs during decision-making, we recorded neurons from the human pre-supplementary motor area (preSMA), ventromedial prefrontal cortex and dorsal anterior cingulate. Unlike the other areas, preSMA neurons not only represented separate pre-decision variables for each choice option but also encoded an integrated utility signal for each choice option and, subsequently, the decision itself. Post-decision encoding of variables for the chosen option was more widely distributed and especially prominent in the ventromedial prefrontal cortex. Our findings position the human preSMA as central to the implementation of value-based decisions.
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