ArticleCerebral cortex (New York, N.Y. : 1991)2023
Daily artificial gravity is associated with greater neural efficiency during sensorimotor adaptation.
Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Review
- Neurophysiological effects of partial gravity on bimanual control: a parabolic flight study.NPJ microgravity · 2026Article
- Sensory network segregation as a predictor of post spaceflight balance impairments and sensory re-weighting.NPJ microgravity · 2025Article
- Thirty minutes of daily artificial gravity does not mitigate head down tilt induced brain activity changes during cognitive task performance.Frontiers in neurology · 2025Article
- Daily artificial gravity partially mitigates vestibular processing changes associated with head-down tilt bedrest.NPJ microgravity · 2024Article
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
Altered vestibular signaling and body unloading in microgravity results in sensory reweighting and adaptation. Microgravity effects are well-replicated in head-down tilt bed rest (HDBR). Artificial gravity (AG) is a potential countermeasure to mitigate the effects of microgravity on human physiology and performance. We examined the effectiveness of daily AG for mitigating brain and/or behavioral changes in 60 days of HDBR. One group received AG for 30 minutes daily (AG; n = 16) and a control group spent the same time in HDBR but received no AG (CTRL; n = 8). All participants performed a sensorimotor adaptation task five times during fMRI scanning: twice prior to HDBR, twice during HDBR, and once following HDBR. The AG group showed similar behavioral adaptation effects compared with the CTRLs. We identified decreased brain activation in the AG group from pre to late HDBR in the cerebellum for the task baseline portion and in the thalamus, calcarine, cuneus, premotor cortices, and superior frontal gyrus in the AG group during the early adaptation phase. The two groups also exhibited differential brain-behavior correlations. Together, these results suggest that AG may result in a reduced recruitment of brain activity for basic motor processes and sensorimotor adaptation. These effects may stem from the somatosensory and vestibular stimulation that occur with AG.
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Registered trials
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