Evidence map›Paper›PMID 36958702›Full record

ArticleContemporary clinical trials2023

Evaluation of the efficacy and mechanisms of a novel intervention for chronic pain tailored to people with HIV: The STOMP protocol.

Katie Fitzgerald Jones, Matthew J Bair, Sarah Margaret Orris, Mallory Johnson, Jane M Liebschutz, William Demonte, Olivio J Clay, Amy L Durr, Claire E Farel, Deana Agil and 10 more

Registry-linked trialOpen access · greenAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03692611 (Evaluation of the Efficacy and Mechanisms of a Novel Intervention for Chronic Pain Tailored to People Living With HIV), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03692611 nacompletednot on this map

Evaluation of the Efficacy and Mechanisms of a Novel Intervention for Chronic Pain Tailored to People Living With HIV

TypeinterventionalSponsorUniversity of PittsburghRan2019 to 2025Enrolled278ConditionsChronic PainArmsSkills TO Manage Pain (STOMP), Comparison group
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Neuropathogenesis of HIV and emerging therapeutic targets.Expert opinion on therapeutic targets · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 1 country.

Katie Fitzgerald JonesCenter for Aging and Serious Illness, Division of Geriatrics and Palliative Care, Massachusetts General Hospital, Boston, MA, USA. Electronic address: kfjones@mgh.harvard.edu.
Matthew J BairVA HSR&D Center for Health Information and Communication, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Sarah Margaret OrrisDivision of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Mallory JohnsonCenter for AIDS Prevention Studies, University of San Francisco, San Francisco, CA, USA.
Jane M LiebschutzDivision of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
William DemonteVirginia Mason Franciscan Health, Bonney Lake, WA, USA.
Olivio J ClayDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Amy L DurrDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Claire E FarelDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Deana AgilDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Greer BurkholderDivision of Infectious Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Bernadette JohnsonDivision of Infectious Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Kendall ConderDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Mireille LeoneDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sonia NapravnikDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Tammi ThomasDivision of Infectious Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Lindsay BrowneDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kiko KingDivision of Infectious Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
LaToya MullenDivision of Infectious Diseases, Department of Medicine, Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jessica MerlinDivision of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
University of North Carolina at Chapel Hill · USUniversity of Alabama at Birmingham · USUniversity of Pittsburgh · USFranciscan Health · USIndiana University School of MedicineMassachusetts General Hospital · USSan Francisco AIDS Foundation · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Evaluation of the efficacy and mechanisms of a novel intervention for chronic pain tailored to people living with HIVR01MH115754 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MERLIN, JESSICA S · 2018 to 2022
$3.1M
NIAID NIH HHS P30 AI050410NIMH NIH HHS R01 MH115754
6 · The paper itself

Abstract

backgroundBehavioral interventions for chronic pain among people with HIV (PWH) are understudied, with great potential to improve pain and function. Chronic pain is an important comorbidity that affects between 30% and 85% of PWH and is associated with greater odds of functional impairment, increased emergency room utilization, suboptimal retention in HIV care, and failure to achieve virologic suppression. However, to date, there are few effective and scalable interventions for chronic pain in PWH.

objectiveThis manuscript outlines the protocol for a randomized control trial of a novel theory-based pain self-management intervention, "Skills TO Manage Pain" (STOMP), developed for and tailored to PWH versus enhanced usual care controls. STOMP is a 12-week intervention developed from prior work on pain self-management in PWH and rigorous intervention mapping. The STOMP intervention has three major components: group sessions, one-on-one pain self-management sessions, and peer leaders.

methodsSTOMP is a 2-arm randomized trial conducted with PWH with chronic pain. The trial compares STOMP, a theory-based intervention tailored to improving chronic pain in PWH, with a comparison group receiving enhanced usual care effectiveness on pain and HIV proximal outcome measures. The proposed sample size is 280 PWH recruited from two high-volume Center for AIDS Research Network of Integrated Clinical Systems clinical sites.

resultsStudy procedures are ongoing, and results will be recorded in future manuscripts.

conclusionThe study will generate evidence on the effectiveness of STOMP with the potential to dramatically change chronic pain treatment for PWH.

trial registrationclinicialtrials.gov, Clinical Trials Registration # NCT03692611https://clinicaltrials.gov/ct2/show/NCT03692611?term=STOMP&cond=Hiv&draw=2&rank=1.

Indexed as

Chronic PainHIV InfectionsSelf-ManagementComorbidityHumansPain ManagementRandomized Controlled Trials as TopicHIVPainSelf-managementSocial cognitive theory

Identifiers

PMID36958702
PMCPMC12101796
OpenAlexW4328102503

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.