Evidence map›Paper›PMID 36958701›Full record

ArticleThe Journal of hospital infection2023

Monkeypox virus isolation from longitudinal samples from four patients to infer risk of onwards transmission: an interim analysis.

H Callaby, K Emery, M Killip, T Rampling, K S Richards, C F Houlihan

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of hospital infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

H CallabyRare and Imported Pathogens Laboratory, UKHSA, Porton Down, UK; Aberdeen Royal Infirmary, Aberdeen, UK. Electronic address: helen.callaby@nhs.scot.
K EmeryHigh Containment & Biological Services, Salisbury, UK.
M KillipHigh Containment & Biological Services, Salisbury, UK.
T RamplingRare and Imported Pathogens Laboratory, UKHSA, Porton Down, UK; The Hospital for Tropical Diseases, University College London Hospital, London, UK; NIHR University College London Hospitals BRC, London, UK.
K S RichardsHigh Containment & Biological Services, Salisbury, UK; Faculty of Health and Life Sciences, Oxford Brookes University, Headington Campus, Oxford, UK.
C F HoulihanRare and Imported Pathogens Laboratory, UKHSA, Porton Down, UK; Clinical Virology, University College London Hospital, London, UK; Department of Infection and Immunity, University College London, London, UK.
University College Hospital · GBAberdeen Royal Infirmary · GBOxford Brookes University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monkeypox virus (mpxv) is a DNA virus in the Orthopoxvirus genus which causes Mpox (previously monkeypox). Symptoms include fever, lymphadenopathy and vesicular lesions. There is limited evidence for the duration of mpxv infectivity. This study used cell culture as a proxy for infectivity. Clinical samples from four patients with Mpox were inoculated into African green monkey kidney (Vero E6) cells and monitored for cytopathic effects (CPE). From one patient, infectious mpxv was recovered 25 days after illness onset. Infectious virus was not isolated from samples with an Orthopoxvirus polymerase chain reaction (PCR) Ct value over 31.0, nor from urine.

Indexed as

Mpox, MonkeypoxChlorocebus aethiopsMonkeypox virusPolymerase Chain ReactionInfectivityMonkeypoxMpoxTransmissionViral culture

Identifiers

PMID36958701
PMCPMC10029343
OpenAlexW4328053038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.