Evidence map›Paper›PMID 36958668›Full record

ArticleThe spine journal : official journal of the North American Spine Society2023

Biopsychosocial sequelae and recovery trajectories from whiplash injury following a motor vehicle collision.

J M Elliott, D M Walton, S R Albin, D M Courtney, G P Siegmund, L J Carroll, K A Weber, A C Smith

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The spine journal : official journal of the North American Spine Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02157038 (Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02157038 nacompletednot on this map

Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries

TypeinterventionalSponsorNorthwestern UniversityRan2014 to 2020Enrolled97ConditionsWhiplash Associated Disorders, WAD, WhiplashArmsPedometer, MRI
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

J M ElliottFaculty of Medicine and Health, University of Sydney, Northern Sydney Local Health District, The Kolling Institute, 10 Westbourne St, St Leonards, New South Wales, 2065, Australia; Physical Therapy & Human Movement Sciences, Feinberg School of Medicine, Northwestern University, 645 N Michigan Ave, Chicago, IL 60611, USA. Electronic address: jim.elliott@sydney.edu.au.
D M WaltonFaculty of Health Sciences, School of Physical Therapy, Western University Canada Schulich School of Medicine and Dentistry, 1151 Richmond St, London, Ontario N6A 5C1, Canada; Department of Psychiatry, Western University Canada, 151 Richmond St, London, Ontario N6A 5C1, Canada.
S R AlbinSchool of Physical Therapy, Regis University, 3333 Regis Boulevard Denver, CO 80221-1099, USA.
D M CourtneyDepartment of Emergency Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.
G P SiegmundMEA Forensics, 11151 Horseshoe Way, Richmond, British Columbia V7A 4S5, Canada.
L J CarrollSchool of Public Health, University of Alberta, 11405 87 Ave NW, Edmonton, Alberta T6G 1C9, Canada.
K A WeberDivision of Pain Medicine, Stanford School of Medicine, 900 Blake Wilbur Dr, Palo Alto, CA 94304, USA.
A C SmithPhysical Therapy Program, Department of Physical Medicine and Rehabilitation, School of Medicine, University of Colorado, 12631 E 17th Ave, Aurora, CO 80045, USA.
Northwestern University · USRegis University · USStanford Medicine · USThe University of Texas Southwestern Medical Center · USUniversity of Alberta · CAUniversity of Colorado Denver · USWestern University · CA

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)KL2TR001424 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2015 to 2023
$8.1M
Neuromuscular Mechanisms Underlying Poor Recovery from Whiplash InjuriesR01HD079076 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI COURTNEY, D. MARK, ELLIOTT, JAMES MATTHEW · 2014 to 2018
$1.6M
Neuroimaging-Based Brain and Spinal Cord Biomarkers for Cervical RadiculopathyK23NS104211 · NINDS · STANFORD UNIVERSITY · PI WEBER, KENNETH ARNOLD · 2018 to 2022
$875k
Improving mechanistic understanding of responsiveness to spinal cord stimulation after spinal cord injuryK01HD106928 · NICHD · UNIVERSITY OF COLORADO DENVER · PI SMITH, ANDREW CRAIG · 2022 to 2025
$508k
NCATS NIH HHS KL2 TR001424NICHD NIH HHS K01 HD106928NICHD NIH HHS R01 HD079076NINDS NIH HHS K23 NS104211NINDS NIH HHS L30 NS108301
6 · The paper itself

Abstract

background contextFive out of 10 injured in a motor vehicle collision (MVC) will develop persistent pain and disability. It is unclear if prolonged symptoms are related to peritraumatic pain/disability, psychological distress, muscle fat, lower extremity weakness. PURPOSE: To test if widespread muscle fat infiltration (MFI) was (1) unique to those with poor recovery, (2) present in the peritraumatic stage, (3) related to known risk factors. STUDY DESIGN/

settingA cohort study, single-center academic hospital. PATIENT SAMPLES: A total of 97 men and women (age 18-65) presenting to an urban academic emergency medicine department following MVC, but not requiring inpatient hospitalization. PRIMARY OUTCOME MEASURE: Neck disability at 12-months.

methodsParticipants underwent magnetic resonance imaging (MRI) to quantify neck and lower extremity MFI, completed questionnaires on pain/disability and psychological distress (< 1-week, 2-weeks, 3-, and 12-months) and underwent maximum volitional torque testing of their lower extremities (2-weeks, 3-, and 12-months). Percentage score on the Neck Disability Index at 12-months was used for a model of (1) Recovered (0%-8%), (2) Mild (10%-28%), and (3) Moderate/Severe (≥ 30%). This model was adjusted for BMI and age.

resultsSignificant differences for neck MFI were revealed, with the Recovered group having significantly lower neck MFI than the Mild and Moderate/Severe groups at all time points. The Mild group had significantly more leg MFI at 12-months (p=.02) than the Recovered group. There were no other significant differences at any other time point. Lower extremity torques revealed no group differences. The Traumatic Injury Distress Scale (TIDS) and MFI of the neck at 1-week postinjury significantly predicted NDI score at 12-months.

conclusionsHigher neck MFI and distress may represent a risk factor though it is unclear whether this is a pre-existing phenotype or result of the trauma.

trial registrationClinicalTrials.gov Identifier: NCT02157038.

Indexed as

Whiplash InjuriesCohort StudiesDisease ProgressionFemaleHumansMotor VehiclesNeckPainDistressMRIMusclePainTraumaWhiplash

Identifiers

PMID36958668
PMCPMC10330498
OpenAlexW4328103248

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.