ArticleImmunity2023
A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans.
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Article in Immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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58citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
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Who cites it
58 citing papers in PubMed, 75 citations in OpenAlex.
- Temporal and transcriptional programming of effector memory B cells shapes vaccine platform-dependent humoral immunity.iScience · 2026Article
- Interferon-Mediated Regulation of Memory B Cell Identity and Function.Immunological reviews · 2026Review
- The Developmental and Functional Implications of Age-Associated B Cells (ABCs) Across Tissue Microenvironments.Immunological reviews · 2026Review
- Unraveling the layers of epigenetic control in respiratory antiviral defense.Journal of virology · 2026Review
- Atypical B cells and inflammatory profiles delineate immunity to influenza vaccination in First Nations and non-Indigenous people with chronic multimorbidity.Nature communications · 2026Article
- SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children.Nature communications · 2026Article
- The Presence of CD11c+ B Cells with Potent Effector Memory Phenotype in Lung Adenocarcinoma Correlates with Overall Patient Survival.Cancer immunology research · 2026Article
- IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination.EMBO molecular medicine · 2026Article
- Meeting Report: Fourth Correlates of Protection for Next Generation Influenza Vaccines.Influenza and other respiratory viruses · 2026Article
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- Robust effector memory features of human T-betiScience · 2026Article
- IFNγ-induced IRF1 synergizes with TLR7 signals to tune the IRF4-IRF8 axis and drive pathogenic effector B cell fate.bioRxiv : the preprint server for biology · 2026Article
- Extrafollicular and other non-germinal center B cell responses.Journal of immunology (Baltimore, Md. : 1950) · 2026Review
- Unveiling an Immunological Mystery: Deciphering the Durability Divide in Vaccine-Elicited Antibody Responses.Current HIV research · 2026Review
- Article
- Article
- Pediatric T cell and B cell responses to SARS-CoV-2 infection.JCI insight · 2025Article
- Article
- Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation.Science translational medicine · 2025Article
- SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children.Research square · 2025Article
Corrections and comments
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Authors and funding
17 authors at 2 institutions in 1 country.
Anoma NelloreDepartment of Medicine, Division of Infectious Disease, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: anellore@uabmc.edu.
Esther ZumaqueroDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Christopher D ScharerDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Christopher F FucileInformatics Institute, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Christopher M TiptonDepartment of Medicine, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA 30322, USA.
R Glenn KingDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Tian MiDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Betty MousseauDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
John E BradleyDepartment of Medicine, Division of Clinical Immunology and Rheumatology at The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Fen ZhouDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Stuti MutnejaDepartment of Medicine, Division of Infectious Disease, The University of Alabama at Birmingham, Birmingham, AL 35294, USA; ImmuneID, Waltham, MA 02451, USA.
Paul A GoepfertDepartment of Medicine, Division of Infectious Disease, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jeremy M BossDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Troy D RandallDepartment of Medicine, Division of Clinical Immunology and Rheumatology at The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Ignacio SanzDepartment of Medicine, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Alexander F RosenbergDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA; Informatics Institute, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Frances E LundDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address: flund@uab.edu.
University of Alabama at Birmingham · USEmory University · US
Funding
XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9MVirology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Latesha Ellen Elopre · 1988 to 2026
$84.1MUAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4MRegulation of Pathogenic Plasma Cells in Human SLEP01AI125180 · NIAID · EMORY UNIVERSITY · PI Ignacio E. Sanz · 2016 to 2026
$28.2MTissue and organ specific human B cell immunity: Supplement - Metabolic Risk Factors and Inflammation in PASC DevelopmentU19AI142737 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LUND, FRANCES E. · 2019 to 2023
$19.7MVirus-induced Cell Fate Decisions in Anti-Viral ImmunityU19AI109962 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LUND, FRANCES E. · 2014 to 2018
$11.6MROS Modulation of Innate and Adaptive Immunity in RAP30AR048311 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MOUNTZ, JOHN D · 2001 to 2017
$9.5MEpigenetic instruction of memory B cell function and reactivationR01AI148471 · NIAID · EMORY UNIVERSITY · PI SCHARER, CHRISTOPHER D · 2020 to 2024
$1.9MAssessing Flu-specific Humoral Immunity in Human Lung after Ex Vivo Lung PerfusionR21AI152006 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI NELLORE, ANOMA, RANDALL, TROY D · 2020 to 2021
$408kNCATS NIH HHS UL1 TR001417NCI NIH HHS P30 CA013148NIAID NIH HHS P01 AI125180NIAID NIH HHS P30 AI027767NIAID NIH HHS R01 AI148471NIAID NIH HHS R21 AI152006NIAID NIH HHS U19 AI109962NIAID NIH HHS U19 AI142737NIAMS NIH HHS P30 AR048311
Abstract
Seasonal influenza vaccination elicits hemagglutinin (HA)-specific memory B (Bmem) cells, and although multiple Bmem cell populations have been characterized, considerable heterogeneity exists. We found that HA-specific human Bmem cells differed in the expression of surface marker FcRL5 and transcriptional factor T-bet. FcRL5
Indexed as
Influenza, HumanInfluenza VaccinesAntibodies, ViralAntibody FormationHumansImmunologic MemoryMemory B CellsVaccinationAntibodies, ViralInfluenza Vaccinesdurable immunityinfluenza vaccinationmemory B cellsplasmablastsT-bet
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.