Evidence map›Paper›PMID 36958168›Full record

ArticleJournal of infection and public health2023

Real-life lack of evidence of viable SARS-CoV-2 transmission via inanimate surfaces: The SURFACE study.

José Camilla Sammartino, Marta Colaneri, Cecilia Bassoli, Mariaelena Ceresini, Antonio Piralla, Alessandro Ferrari, Elena Percivalle, Fausto Baldanti, Raffaele Bruno, Mario U Mondelli

Abstract read
In one paragraph

Article in Journal of infection and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

José Camilla SammartinoDivision of Microbiology and Virology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Marta ColaneriDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Cecilia BassoliDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Mariaelena CeresiniDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Antonio PirallaDivision of Microbiology and Virology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Alessandro FerrariDivision of Microbiology and Virology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Elena PercivalleDivision of Microbiology and Virology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Fausto BaldantiDivision of Microbiology and Virology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Clinical Surgical Diagnostic & Pediatric Sciences, University of Pavia, Italy.
Raffaele BrunoDivision of Infectious Diseases I, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Clinical Surgical Diagnostic & Pediatric Sciences, University of Pavia, Italy.
Mario U MondelliDepartment of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; Division of Clinical Immunology and Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. Electronic address: mario.mondelli@unipv.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough the potential role of inanimate surfaces in SARS-CoV-2 transmission has yet to be adequately assessed, it is still routine practice to apply deep and expensive environmental disinfection protocols. The aim of this study was to verify the presence of viable virus on different surfaces exposed to droplets released by coughing in SARS-CoV-2 RNA positive patients.

methodsPatients admitted to hospital with a positive SARS-CoV-2 real-time (RT)-PCR swab were asked to cough on steel, cardboard, plastic and their hands. Surfaces were tested at baseline (T

resultsTen RNA-positive patients were enrolled into the study. The median cycle threshold value was 20.7 (range 13-28.3). Nasopharyngeal swabs from 3 of the patients yielded viable virus 2-10 days post-inoculation. However, in none of the patients was it possible to isolate viable SARS-CoV-2 from sputum under identical experimental conditions. A CPE was instead already visible using laboratory-propagated SARS-CoV-2 strains at 20', 60', 180' while an effect at 24 h required a 6-day incubation.

conclusionThe evidence emerging from this real-life study suggests that droplets delivered by SARS-CoV-2 infected patients on common inanimate surfaces did not contain viable virus. In contrast, and in line with several laboratory-based experiments, in vitro adapted viruses could survive and grow on the same fomites.

Indexed as

COVID-19SARS-CoV-2FomitesHospitalsHumansRNA, ViralRNA, ViralContaminationInanimate surfacesSARS-CoV-2Viable virus

Identifiers

PMID36958168
PMCPMC10027289

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.