Evidence map›Paper›PMID 36958098›Full record

ArticleTalanta2023

Paper microfluidics with deep learning for portable intelligent nucleic acid amplification tests.

Hao Sun, Wantao Xie, Yi Huang, Jin Mo, Hui Dong, Xinkai Chen, Zhixing Zhang, Junyi Shang

Open access · greenAbstract read
In one paragraph

Article in Talanta, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. An integrated microfluidic system for automatic and self-validated analysis of cervical extracellular vesicle markers PD-L1 and ERBB3.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
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  3. Article
  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Hao SunSchool of Mechanical Engineering and Automation, Fuzhou University, 350108, China; Fujian Provincial Collaborative Innovation Centre of High-End Equipment Manufacturing, 350108, China. Electronic address: sh@fzu.edu.cn.
Wantao XieSchool of Mechanical Engineering and Automation, Fuzhou University, 350108, China; Fujian Provincial Collaborative Innovation Centre of High-End Equipment Manufacturing, 350108, China.
Yi HuangCentre for Experimental Research in Clinical Medicine, Fujian Provincial Hospital, 350001, China.
Jin MoSchool of Mechanical Engineering and Automation, Fuzhou University, 350108, China; Fujian Provincial Collaborative Innovation Centre of High-End Equipment Manufacturing, 350108, China.
Hui DongSchool of Mechanical Engineering and Automation, Fuzhou University, 350108, China; Fujian Provincial Collaborative Innovation Centre of High-End Equipment Manufacturing, 350108, China. Electronic address: hdong@fzu.edu.cn.
Xinkai ChenStar-Net Ruijie Science & Technology Co., Ltd., 350108, China.
Zhixing ZhangSino-German College of Intelligent Manufacturing, Shenzhen Technology University, 518118, China. Electronic address: zhangzhixing@sztu.edu.cn.
Junyi ShangSchool of Automation, Beijing Institute of Technology, 100081, China. Electronic address: shangjunyi@bit.edu.cn.
Fuzhou University · CNBeijing Institute of Technology · CNFujian Provincial Hospital · CNFujian Star-net (China) · CNShenzhen Technology University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During global outbreaks such as COVID-19, regular nucleic acid amplification tests (NAATs) have posed unprecedented burden on hospital resources. Data of traditional NAATs are manually analyzed post assay. Integration of artificial intelligence (AI) with on-chip assays give rise to novel analytical platforms via data-driven models. Here, we combined paper microfluidics, portable optoelectronic system with deep learning for SARS-CoV-2 detection. The system was quite streamlined with low power dissipation. Pixel by pixel signals reflecting amplification of synthesized SARS-CoV-2 templates (containing ORF1ab, N and E genes) can be real-time processed. Then, the data were synchronously fed to the neural networks for early prediction analysis. Instead of the quantification cycle (C

Indexed as

COVID-19Deep LearningArtificial IntelligenceHumansMicrofluidicsNucleic Acid Amplification TechniquesSARS-CoV-2Sensitivity and SpecificityCOVID-19 diagnosisDeep learningNAATPaper microfluidics

Identifiers

PMID36958098
PMCPMC10027307
OpenAlexW4327919048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.