ArticlePloS one2023
Dynamics of two-step reversible enzymatic reaction under fractional derivative with Mittag-Leffler Kernel.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 26 citations in OpenAlex.
- Analysis of variable-order fractional enzyme kinetics model with time delay.Scientific reports · 2025Article
- An efficient discrete Chebyshev polynomials strategy for tempered time fractional nonlinear Schrödinger problems.Journal of advanced research · 2025Article
- High performance computational approach to study model describing reversible two-step enzymatic reaction with time fractional derivative.Scientific reports · 2024Article
- Analysis of a class of fractal hybrid fractional differential equation with application to a biological model.Scientific reports · 2024Article
- Topology degree results on a G-ABC implicit fractional differential equation under three-point boundary conditions.PloS one · 2024Article
- Impact of nanoparticles on vegetable oil as a cutting fluid with fractional ramped analysis.Scientific reports · 2023Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemical kinetics is a branch of chemistry that is founded on understanding chemical reaction rates. Chemical kinetics relates many aspects of cosmology, geology, and even in some cases of, psychology. There is a need for mathematical modelling of these chemical reactions. Therefore, the present research is based on chemical kinetics-based modelling and dynamics of enzyme processes. This research looks at the two-step substrate-enzyme reversible response. In the two step-reversible reactions, substrate combines with enzymes which is further converted into products with two steps. The model is displayed through the flow chart, which is then transformed into ODEs. The Atangana-Baleanu time-fractional operator and the Mittag-Leffler kernel are used to convert the original set of highly nonlinear coupled integer order ordinary differential equations into a fractional-order model. Additionally, it is shown that the solution to the investigated fractional model is unique, limited, and may be represented by its response velocity. A numerical scheme, also known as the Atangana-Toufik method, based on Newton polynomial interpolation technique via MATLAB software, is adopted to find the graphical results. The dynamics of reaction against different reaction rates are presented through various figures. It is observed that the forward reaction rates increase the reaction speed while backward reaction rates reduce it.
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