Evidence map›Paper›PMID 36952265›Full record

ArticleJournal of the American Chemical Society2023

Jaeyoung Kwon, Munhyung Bae, Dávid Szamosvári, Chelsi D Cassilly, Andrew S Bolze, David R Jackson, Ramnik J Xavier, Jon Clardy

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Supplementation with abioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Article
  9. Journal of the American Chemical Society · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Spontaneous Generation of an Endogenous RORγt Agonist.Journal of the American Chemical Society · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. mSystems · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jaeyoung KwonDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.
Munhyung BaeDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.
Dávid SzamosváriDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.ORCID 0000-0002-2896-1976
Chelsi D CassillyDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.
Andrew S BolzeBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.
David R JacksonDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.
Ramnik J XavierBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.
Jon ClardyDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, Massachusetts 02115, United States.ORCID 0000-0003-0213-8356
Harvard University · USBroad Institute · USGachon University · KR

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
Identification and characterization of gut microbial bioactive molecules that determine predisposition to autoimmune disease and atopyR01AT009708 · NCCIH · HARVARD MEDICAL SCHOOL · PI CLARDY, JON, XAVIER, RAMNIK J · 2017 to 2021
$3.3M
NCCIH NIH HHS R01 AT009708NIDDK NIH HHS P30 DK043351
6 · The paper itself

Abstract

Some members of the human gut microbiota profoundly influence their host's physiology, health, and therapeutic responses, but the responsible molecules and mechanisms are largely unknown. As part of a project to identify immunomodulators produced by gut microbes, we analyzed the metabolome of

Indexed as

ActinobacteriaToll-Like Receptor 2Dendritic CellsHumansHydrogen-Ion ConcentrationLipidsMicrobiotaLipidsToll-Like Receptor 2

Identifiers

PMID36952265
PMCPMC10080676
OpenAlexW4360601048

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.