Evidence map›Paper›PMID 36951998›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2023

Temperature alters the inotropic, chronotropic and proarrhythmic effects of histamine in atrial muscle preparations from humans and H

Robert J R Hoffmann, Ulrich Gergs, Britt Hofmann, Uwe Kirchhefer, Joachim Neumann

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Temperature alters the inotropic and chronotropic effect of DNaunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
  2. Article
  3. Studies on the mechanisms of action of MR33317.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Robert J R HoffmannInstitut Für Pharmakologie und Toxikologie, Medizinische Fakultät, Martin-Luther-Universität Halle-Wittenberg, 06097, Halle, Germany.
Ulrich GergsInstitut Für Pharmakologie und Toxikologie, Medizinische Fakultät, Martin-Luther-Universität Halle-Wittenberg, 06097, Halle, Germany.
Britt HofmannMedizinische Fakultät, Herzchirurgie, Martin-Luther-Universität Halle-Wittenberg, 06097, Halle, Germany.
Uwe KirchheferInstitut für Pharmakologie und Toxikologie, Medizinische Fakultät, Westfälische Wilhelms-Universität, Domagkstr. 12, 48149, Münster, Germany.
Joachim NeumannInstitut Für Pharmakologie und Toxikologie, Medizinische Fakultät, Martin-Luther-Universität Halle-Wittenberg, 06097, Halle, Germany. joachim.neumann@medizin.uni-halle.de.
Martin Luther University Halle-Wittenberg · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated whether hypothermia and hyperthermia can alter the efficacy and potency of histamine at increasing the force of cardiac contractions in mice that overexpress the human H

Indexed as

Atrial FibrillationHypothermiaAnimalsHeart AtriaHeart RateHistamineHumansMiceMyocardial ContractionMyocytes, CardiacTemperatureHistamineArrhythmiaChronotropyH2 receptorHistamineHuman phospholambanHyperthermiaHypothermiaInotropy

Identifiers

PMID36951998
PMCPMC10409711
OpenAlexW4360600165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.