Evidence map›Paper›PMID 36951552›Full record

ReviewJournal of bacteriology2023

Bacteria in Fluid Flow.

Gilberto C Padron, Alexander M Shuppara, Jessica-Jae S Palalay, Anuradha Sharma, Joseph E Sanfilippo

Abstract readReview
In one paragraph

Review in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Detoxification of host-relevant HbioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Flagellum-driven motility enhancesApplied and environmental microbiology · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Free-swimming bacteria transcriptionally respond to shear flow.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Shear force enhances adhesion ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gilberto C PadronDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Alexander M ShupparaDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Jessica-Jae S PalalayDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Anuradha SharmaDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Joseph E SanfilippoDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

Funding

Mechanobehavior of Pseudomonas aeruginosa in shear flowK22AI151263 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SANFILIPPO, JOSEPH · 2021 to 2022
$267k
NIAID NIH HHS K22 AI151263
6 · The paper itself

Abstract

Bacteria thrive in environments rich in fluid flow, such as the gastrointestinal tract, bloodstream, aquatic systems, and the urinary tract. Despite the importance of flow, how flow affects bacterial life is underappreciated. In recent years, the combination of approaches from biology, physics, and engineering has led to a deeper understanding of how bacteria interact with flow. Here, we highlight the wide range of bacterial responses to flow, including changes in surface adhesion, motility, surface colonization, quorum sensing, virulence factor production, and gene expression. To emphasize the diversity of flow responses, we focus our review on how flow affects four ecologically distinct bacterial species: Escherichia coli, Staphylococcus aureus, Caulobacter crescentus, and Pseudomonas aeruginosa. Additionally, we present experimental approaches to precisely study bacteria in flow, discuss how only some flow responses are triggered by shear force, and provide perspective on flow-sensitive bacterial signaling.

Indexed as

Caulobacter crescentusStaphylococcal InfectionsHumansPseudomonas aeruginosaQuorum SensingVirulence FactorsVirulence Factorsadhesionbacteriacolonizationfluid flowgene expressionmechanobiologymechanosensingmotilityquorum sensingvirulence

Identifiers

PMID36951552
PMCPMC10127660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.